Reactome | GNRH1 [extracellular region]

GNRH1 [extracellular region]

Stable Identifier

R-BTA-873934

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

GNRH1(24-33), Q0VBW7

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (q) signalling events (Bos taurus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
        
        GNRHR:GNRH1,2 [plasma membrane] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
        
        GNRHR:GNRH1,2 [plasma membrane] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
        
        GNRHR:GNRH1,2 [plasma membrane] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
        
        GNRHR:GNRH1,2 [plasma membrane] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
      - The Ligand:GPCR:Gq complex dissociates (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
        
        GNRHR:GNRH1,2 [plasma membrane] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Hormone ligand-binding receptors (Bos taurus)
        
        GNRHR binds GNRH1,2 (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)
        
        GNRHR:GNRH1,2 [plasma membrane] (Bos taurus)
        
        GNRH1,2 [extracellular region] (Bos taurus)
        
        GNRH1 [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:Q0VBW7

Gene Names

GNRH1

Reference Genes

BioGPS Gene:768325 GNRH1

ENSEMBL:ENSBTAG00000000164.3

KEGG Gene (Bos taurus):768325 GNRH1

Monarch:768325 GNRH1

NCBI Gene:768325 GNRH1

Reference Transcript

Other Identifiers

768325

GO:0000003

GO:0005179

GO:0005183

GO:0005576

GO:0005615

GO:0007165

GO:0007275

GO:0010468

GO:0022414

GO:0023052

GO:0030154

GO:0031530

GO:0045471

GO:0048018

GO:0048545

GO:0048856

GO:0048870

GO:0098772

GO:2000354

GO:2001223

Participates

as a member of

GNRH1,2 [extracellular region] (Bos taurus)

Inferred From

GNRH1(24-33) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001071605.1, XP_005210348.1

OpenTargets

ENSG00000147437

Ensembl

ENSBTAT00000000188, ENSBTAP00000000188, ENSBTAG00000000164

VGNC

29481