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APP [extracellular region]
Stable Identifier
R-BTA-879340
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
extracellular region
Synonyms
APP(672-713), A0A3Q1LUG2
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Innate Immune System (Bos taurus)
Advanced glycosylation endproduct receptor signaling (Bos taurus)
Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
TRAF6 mediated NF-kB activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (q) signalling events (Bos taurus)
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
FPR2 ligands [extracellular region] (Bos taurus)
APP [extracellular region] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1LUG2
Gene Names
APP
Reference Genes
BioGPS Gene:280722 APP
ENSEMBL:ENSBTAG00000017753.6
Monarch:280722 APP
NCBI Gene:280722 APP
UCSC:A0A3Q1LUG2 APP
Reference Transcript
RefSeq:XM_005201137.2 APP
Other Identifiers
280722
GO:0000086
GO:0000278
GO:0000978
GO:0001774
GO:0001967
GO:0002265
GO:0002376
GO:0003677
GO:0004867
GO:0005102
GO:0005576
GO:0005615
GO:0005634
GO:0005641
GO:0005737
GO:0005768
GO:0005769
GO:0005783
GO:0005790
GO:0005794
GO:0005798
GO:0005886
GO:0005905
GO:0005911
GO:0006355
GO:0006417
GO:0006629
GO:0006878
GO:0006897
GO:0006915
GO:0006979
GO:0007018
GO:0007219
GO:0007409
GO:0007417
GO:0007611
GO:0007612
GO:0007617
GO:0007626
GO:0008021
GO:0008088
GO:0008201
GO:0008203
GO:0008285
GO:0008344
GO:0008542
GO:0009986
GO:0010468
GO:0010628
GO:0010629
GO:0010800
GO:0010971
GO:0012501
GO:0012505
GO:0014005
GO:0016020
GO:0016071
GO:0016192
GO:0016199
GO:0016322
GO:0016358
GO:0019899
GO:0019901
GO:0022414
GO:0030134
GO:0030136
GO:0030154
GO:0030182
GO:0030198
GO:0030424
GO:0030425
GO:0030426
GO:0030546
GO:0030900
GO:0031175
GO:0031410
GO:0031594
GO:0032722
GO:0032731
GO:0032755
GO:0032760
GO:0033138
GO:0034330
GO:0035235
GO:0035253
GO:0040014
GO:0042802
GO:0042995
GO:0043005
GO:0043197
GO:0043198
GO:0043204
GO:0043226
GO:0043235
GO:0045121
GO:0045177
GO:0045202
GO:0045665
GO:0045821
GO:0045931
GO:0045944
GO:0046330
GO:0046872
GO:0046914
GO:0048018
GO:0048143
GO:0048169
GO:0048471
GO:0048669
GO:0048786
GO:0048856
GO:0050729
GO:0050730
GO:0050803
GO:0050808
GO:0050850
GO:0050877
GO:0050885
GO:0050890
GO:0051124
GO:0051233
GO:0051247
GO:0051402
GO:0051425
GO:0051563
GO:0055037
GO:0070050
GO:0070374
GO:0098772
GO:0098815
GO:0120283
GO:0150003
GO:0180011
GO:1900272
GO:1900273
GO:1901224
GO:1904646
GO:1905606
GO:1905908
GO:1990000
GO:1990535
GO:2000406
Participates
as a member of
AGER ligands [extracellular region] (Bos taurus)
FPR2 ligands [extracellular region] (Bos taurus)
Other forms of this molecule
APP [trans-Golgi network membrane]
APP [cytosol]
APP [cytosol]
APP [mitochondrial inner membrane]
APP [extracellular region]
APP [platelet alpha granule lumen]
APP [endosome lumen]
phospho-APP [endoplasmic reticulum lumen]
APP [endoplasmic reticulum lumen]
APP [extracellular region]
Inferred From
APP(672-713) [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_005201194.1
ENSEMBL
ENSBTAT00000085054
,
ENSBTAP00000060984
VGNC
26038
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