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HMGB1 [extracellular region]
Stable Identifier
R-BTA-879382
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
extracellular region
Synonyms
P10103
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Innate Immune System (Bos taurus)
Advanced glycosylation endproduct receptor signaling (Bos taurus)
Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
TRAF6 mediated NF-kB activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Neutrophil degranulation (Bos taurus)
Exocytosis of ficolin-rich granule lumen proteins (Bos taurus)
Ficolin-rich granule lumen proteins [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Exocytosis of secretory granule lumen proteins (Bos taurus)
Secretory granule lumen proteins [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)
AGER ligands:AGER [plasma membrane] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
HMGB1 [extracellular region] (Bos taurus)
External Reference Information
External Reference
UniProt:P10103
Reference Genes
BioGPS Gene:282691
ENSEMBL:ENSBTAG00000018103
KEGG:bta:282691
Monarch:282691
NCBI Gene:282691
UCSC:P10103
Reference Transcript
RefSeq:NM_176612.1
RefSeq:XM_005213558.1
RefSeq:XM_010810664.2
Other Identifiers
282691
GO:0001654
GO:0001773
GO:0001935
GO:0002270
GO:0002281
GO:0002318
GO:0002376
GO:0002643
GO:0002840
GO:0003677
GO:0003690
GO:0003723
GO:0003725
GO:0003727
GO:0005125
GO:0005615
GO:0005634
GO:0005737
GO:0005768
GO:0005769
GO:0005975
GO:0005980
GO:0006091
GO:0006281
GO:0006284
GO:0006325
GO:0006351
GO:0006355
GO:0006366
GO:0010508
GO:0010858
GO:0030099
GO:0030154
GO:0030295
GO:0030324
GO:0031410
GO:0032727
GO:0032728
GO:0032731
GO:0032755
GO:0032760
GO:0034137
GO:0034145
GO:0035767
GO:0043005
GO:0043226
GO:0045089
GO:0045639
GO:0045819
GO:0045944
GO:0048018
GO:0048856
GO:0048870
GO:0051384
GO:0070374
GO:0071222
GO:0071639
GO:0090303
GO:0098761
GO:0098772
GO:1901224
GO:1903672
GO:1905455
GO:2000819
Participates
as a member of
Ficolin-rich granule lumen proteins [extracellular region] (Bos taurus)
Secretory granule lumen proteins [extracellular region] (Bos taurus)
AGER ligands [extracellular region] (Bos taurus)
Other forms of this molecule
HMGB1 [ficolin-1-rich granule lumen]
HMGB1 [secretory granule lumen]
HMGB1 [nucleoplasm]
HC23,45-HMGB1 [extracellular region]
Inferred From
HMGB1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_788785.1
,
XP_005213615.1
,
XP_010808966.1
ENSEMBL
ENSBTAP00000024094
,
ENSBTAT00000024094
VGNC
53816
HMDB Protein
HMDBP13739
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