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UBE2D1 [cytosol]
Stable Identifier
R-BTA-8864160
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
Ub-C85-UBE2D1, Q2TA10
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by CSF3 (G-CSF) (Bos taurus)
Inactivation of CSF3 (G-CSF) signaling (Bos taurus)
SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Protein ubiquitination (Bos taurus)
E3 ubiquitin ligases ubiquitinate target proteins (Bos taurus)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Bos taurus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Bos taurus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
RNF181 binds BCL10 and Ubiquitin:E2 (Bos taurus)
RNF181:BCL10:Ub:E2 [cytoplasm] (Bos taurus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Bos taurus)
Ub-UBE2D1,2,3,UBE2E1,UBE2N [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Bos taurus)
Ub-UBE2D1,2,3,UBE2E1,UBE2N [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
RNF181 polyubiquinates BCL10 (Bos taurus)
RNF181:BCL10:Ub:E2 [cytoplasm] (Bos taurus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Bos taurus)
Ub-UBE2D1,2,3,UBE2E1,UBE2N [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Bos taurus)
Ub-UBE2D1,2,3,UBE2E1,UBE2N [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Bos taurus)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Bos taurus)
Ub:E2 (UBA1 substrate) [cytosol] (Bos taurus)
Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Bos taurus)
Ub:E2 (UBA6 substrate) [cytosol] (Bos taurus)
Ub-conjugated E2 enzyme (UBA6 substrate) [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Protein localization (Bos taurus)
Peroxisomal protein import (Bos taurus)
PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Bos taurus)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Bos taurus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Bos taurus)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Bos taurus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Bos taurus)
Ub:UBE2D1,2,3 [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
TNF signaling (Bos taurus)
Regulation of TNFR1 signaling (Bos taurus)
MIB2 binds CFLAR (Bos taurus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Bos taurus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Bos taurus)
Ub:UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
MIB2 ubiquitinates CFLAR (Bos taurus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Bos taurus)
Ub:UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
MIB2 ubiquitinates CYLD at K338, K530 (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Bos taurus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Bos taurus)
Ub:UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
UBE2D1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q2TA10
Gene Names
UBE2D1
Reference Genes
BioGPS Gene:535287 UBE2D1
ENSEMBL:ENSBTAG00000020796
ENSEMBL:ENSBTAG00000020796.6 UBE2D1
KEGG Gene (Bos taurus):535287 UBE2D1
Monarch:535287 UBE2D1
NCBI Gene:535287 UBE2D1
Reference Transcript
RefSeq:NM_001038167.1 UBE2D1
Other Identifiers
535287
GO:0000151
GO:0000166
GO:0003824
GO:0004842
GO:0005524
GO:0005634
GO:0005737
GO:0006511
GO:0016567
GO:0016740
GO:0030163
GO:0031625
GO:0036211
GO:0043226
GO:0061631
GO:0070936
GO:0140096
Participates
as a member of
Ub-conjugated E2 enzyme (UBA6 substrate) [cytosol] (Bos taurus)
Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Bos taurus)
Ub-UBE2D1,2,3,UBE2E1,UBE2N [cytosol] (Bos taurus)
Ub-C85-UBE2D1,2,3 [cytosol] (Bos taurus)
as an output of
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Bos taurus)
MIB2 ubiquitinates CFLAR (Bos taurus)
MIB2 ubiquitinates CYLD at K338, K530 (Bos taurus)
as a component of
Ub:UBE2D1 [cytosol] (Bos taurus)
Other forms of this molecule
UBE2D1 [nucleoplasm]
UBE2D1 [cytosol]
Inferred From
Ub-C85-UBE2D1 [cytosol]
(Homo sapiens)
Modified Residues
Name
S-(glycyl)-L-cysteine (Cys-Gly) at 85 (in Homo sapiens)
Coordinate
85
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_001033256.1
OpenTargets
ENSG00000072401
IntEnz
2.3.2.24
Ensembl
ENSBTAT00000055368
,
ENSBTAG00000020796
,
ENSBTAP00000051358
VGNC
36579
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