Reactome | phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]

phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]

Stable Identifier

R-BTA-8874613

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

A0A3Q1N508

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by Receptor Tyrosine Kinases (Bos taurus)
  - Signaling by MET (Bos taurus)
    - MET promotes cell motility (Bos taurus)
      - MET activates PTK2 signaling (Bos taurus)
        
        SRC phosphorylates PTK2 (Bos taurus)
        
        HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Bos taurus)
        
        HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Bos taurus)
        
        phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1N508

Reference Genes

ENSEMBL:ENSBTAG00000009578.6

ENSEMBL:ENSBTAG00000009578.7

Other Identifiers

GO:0000166

GO:0001525

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005524

GO:0005856

GO:0005886

GO:0005925

GO:0005938

GO:0007155

GO:0007172

GO:0007173

GO:0008284

GO:0016020

GO:0016740

GO:0023052

GO:0030054

GO:0030155

GO:0030335

GO:0036211

GO:0042995

GO:0043197

GO:0043226

GO:0048856

GO:0048870

GO:0050896

GO:0051128

GO:0051239

GO:0065003

GO:0065008

GO:0070161

GO:0140096

Participates

as a component of

HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Bos taurus)

Other forms of this molecule

phospho-pY-PTK2 [cytosol]

phospho-p-Y194,Y397-PTK2 [cytosol]

phospho-p-5Y-PTK2 [cytosol]

phospho-p-5Y,S732-PTK2 [cytosol]

phospho-p-6Y,S732-PTK2 [cytosol]

PTK2(773-1052) [cytosol]

PTK2(1-772) [cytosol]

PTK2 [cytosol]

phospho-p-Y397-PTK2 [cytosol]

phospho-p-6Y-PTK2 [cytosol]

Inferred From

p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 397 (in Homo sapiens)

Coordinate

397

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 194 (in Homo sapiens)

Coordinate

194

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 577 (in Homo sapiens)

Coordinate

577

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 576 (in Homo sapiens)

Coordinate

576

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

Ensembl

ENSBTAP00000065036, ENSBTAG00000009578, ENSBTAT00000085237

VGNC

33518

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