Reactome | RAD51B [nucleoplasm]

RAD51B [nucleoplasm]

Stable Identifier

R-BTA-983271

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

RAD51B, E1BE93

Locations in the PathwayBrowser

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DNA Repair (Bos taurus)

- DNA Double-Strand Break Repair (Bos taurus)
  - Homology Directed Repair (Bos taurus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Bos taurus)
      - HDR through Homologous Recombination (HRR) (Bos taurus)
        
        D-loop extension by DNA polymerases (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Homologous DNA Pairing and Strand Exchange (Bos taurus)
        
        CX3 complex binds D-loop structures (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Bos taurus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Presynaptic phase of homologous DNA pairing and strand exchange (Bos taurus)
        
        BCDX2 complex formation (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        BCDX2 complex stabilizes RAD51 filament (Bos taurus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Resolution of D-Loop Structures (Bos taurus)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Bos taurus)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Bos taurus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        MUS81:EME1,EME2 cleaves D-loop (Bos taurus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Bos taurus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Bos taurus)
        
        BCDX2 complex [nucleoplasm] (Bos taurus)
        
        RAD51B [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BE93

Gene Names

RAD51B

Reference Genes

BioGPS Gene:617007 RAD51B

ENSEMBL:ENSBTAG00000018971.6

KEGG Gene (Bos taurus):617007 RAD51B

Monarch:617007 RAD51B

NCBI Gene:617007 RAD51B

Reference Transcript

RefSeq:NM_001193137.1 RAD51B

Other Identifiers

617007

GO:0000400

GO:0000724

GO:0003677

GO:0003690

GO:0003697

GO:0003824

GO:0005524

GO:0005634

GO:0005657

GO:0005694

GO:0006281

GO:0006310

GO:0008094

GO:0016787

GO:0016887

GO:0033063

GO:0043226

GO:0140097

GO:0140299

GO:0140657

GO:0140664

Participates

as an input of

as a component of

Inferred From

RAD51B [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001180066.1

OpenTargets

ENSG00000182185

Ensembl

ENSBTAT00000025252, ENSBTAG00000018971, ENSBTAP00000025252

VGNC

33685

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