Reactome | mag-1 [nucleoplasm]

mag-1 [nucleoplasm]

Stable Identifier

R-CEL-156658

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

MAGOH, P49029

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA Polymerase II Transcription Termination (Caenorhabditis elegans)
    - Cleavage of mRNA at the 3'-end (Caenorhabditis elegans)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)

Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
- Processing of Capped Intron-Containing Pre-mRNA (Caenorhabditis elegans)
  - Transport of Mature Transcript to Cytoplasm (Caenorhabditis elegans)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Caenorhabditis elegans)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Caenorhabditis elegans)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Caenorhabditis elegans)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
  - mRNA 3'-end processing (Caenorhabditis elegans)
    - Cleavage of mRNA at the 3'-end (Caenorhabditis elegans)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
    - mRNA polyadenylation (Caenorhabditis elegans)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
  - mRNA Splicing (Caenorhabditis elegans)
    - mRNA Splicing - Major Pathway (Caenorhabditis elegans)
      - Formation of the Spliceosomal C complex containing intron lariat (Caenorhabditis elegans)
        
        Spliceosomal B* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal C complex [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal C* complex (Caenorhabditis elegans)
        
        Spliceosomal C complex [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal C* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal P complex and exon ligation (Caenorhabditis elegans)
        
        Spliceosomal C* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal P complex [nucleoplasm] (Caenorhabditis elegans)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Caenorhabditis elegans)
        
        EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Core EJC [nucleoplasm] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [nucleoplasm] (Caenorhabditis elegans)
        
        mag-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P49029

Gene Names

mag-1

Reference Genes

BioGPS Gene:173073 mag-1

ENSEMBL:WBGene00003123

KEGG:cel:CELE_R09B3.5 mag-1

Monarch:173073 mag-1

NCBI Gene:173073 mag-1

UCSC:P49029 mag-1

Wormbase:WBGene00003123

Wormbase:WBGene00003123 mag-1

Reference Transcript

RefSeq:NM_060624.6 mag-1

Other Identifiers

173073

173444_s_at

18472258

A_12_P103791

CE16310

CE_WBGene00003123_A

CGZ0031516

GO:0005515

GO:0005634

GO:0006397

GO:0008380

GO:0016071

GO:0022414

GO:0030154

GO:0035145

GO:0040022

GO:0043226

GO:0048477

GO:0048856

GO:0051028

GO:0071013

GO:0071028

GO:1901046

GO:1905881

R09B3.5

R09B3.5_127-186_0.945_4_C

R09B3.5_211-270_0.956_1_A

R09B3.5_289-348_0.954_2_B

R09B3_5P00125

R09B3_5P00232

R09B3_5P00352

WBGene00003123

cea2.c.05332

Participates

as a component of

Other forms of this molecule

mag-1 [nucleoplasm]

Inferred From

MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)

MAGOH [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

R09B3.5.1, R09B3.5.1, WBGene00003123

PRO

P49029

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