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let-363 [cytosol]
Stable Identifier
R-CEL-165662
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
MTOR, Q95Q95
Locations in the PathwayBrowser
Expand all
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
Active MTORC1 binds the ULK1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
MTORC1 dissociates from ULK complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to starvation (Caenorhabditis elegans)
Amino acids regulate mTORC1 (Caenorhabditis elegans)
RRAGA,B hydrolyzes GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1 binds RHEB:GTP (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
Regulation of TP53 Activity (Caenorhabditis elegans)
Regulation of TP53 Expression and Degradation (Caenorhabditis elegans)
Regulation of TP53 Degradation (Caenorhabditis elegans)
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Costimulation by the CD28 family (Caenorhabditis elegans)
CD28 co-stimulation (Caenorhabditis elegans)
CD28 dependent PI3K/Akt signaling (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
MAF1 translocates to the nucleus (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
MTOR signalling (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Formation of active mTORC1 complex (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1-mediated signalling (Caenorhabditis elegans)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane] (Caenorhabditis elegans)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 complex [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
let-363 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q95Q95
Gene Names
let-363
Reference Genes
BioGPS Gene:172167 let-363
ENSEMBL:WBGene00002583
Monarch:172167 let-363
NCBI Gene:172167 let-363
UCSC:Q95Q95 let-363
Wormbase:WBGene00002583
Reference Transcript
RefSeq:NM_059148.4 let-363
RefSeq:NM_059151.5 let-363
Other Identifiers
172167
174977_at
18450980
188271_at
A_12_P114684
B0261.2
B0261.2a
B0261.2a_3274-3333_0.810_101_C
B0261.2a_7772-7831_0.930_2_A
B0261.2a_8119-8178_0.912_6_B
B0261.2b
B0261_2aP06605
B0261_2aP07005
B0261_2aP07911
CE32559
CE_WBGene00002583_A
CE_WBGene00002583_B
CE_WBGene00002583_C
CGZ0000500
GO:0003824
GO:0004674
GO:0005515
GO:0016301
GO:0016740
GO:0044877
GO:0140096
WBGene00002583
cea2.d.08685
cea2.d.08707
cea2.p.00399
Participates
as a component of
TORC2 complex [cytosol] (Caenorhabditis elegans)
mTORC1 [cytosol] (Caenorhabditis elegans)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
let-363 [nucleoplasm]
Inferred From
MTOR [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_491552.2
,
NP_491549.2
PRO
Q95Q95
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