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SYT1 [plasma membrane]
Stable Identifier
R-CEL-168786
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
plasma membrane
Synonyms
P34693
Locations in the PathwayBrowser
Expand all
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter release cycle (Caenorhabditis elegans)
Acetylcholine Neurotransmitter Release Cycle (Caenorhabditis elegans)
Release of acetylcholine at the synapse (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Dopamine Neurotransmitter Release Cycle (Caenorhabditis elegans)
Release of docked dopamine loaded synaptic vesicle (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
GABA synthesis, release, reuptake and degradation (Caenorhabditis elegans)
Release of GABA at the synapse (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Glutamate Neurotransmitter Release Cycle (Caenorhabditis elegans)
Release of L-Glutamate at the synapse (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Norepinephrine Neurotransmitter Release Cycle (Caenorhabditis elegans)
Release of noradrenaline at the synapse (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Serotonin Neurotransmitter Release Cycle (Caenorhabditis elegans)
Release of docked serotonin loaded synaptic vesicle (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
BAR domain proteins recruit dynamin (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Cargo recognition for clathrin-mediated endocytosis (Caenorhabditis elegans)
STON2 binds SYT proteins (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
Endophilins recruit synaptojanins to the clathrin-coated pit (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
STON2,1:SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT dimers [plasma membrane] (Caenorhabditis elegans)
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
SYT1 [plasma membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P34693
Reference Genes
BioGPS Gene:174120
CTD Gene:174120
ENSEMBL:WBGene00004921
Monarch:174120
NCBI Gene:174120
UCSC:P34693
Wormbase:WBGene00004921
Reference Transcript
RefSeq:NM_001026958.3
Other Identifiers
174120
175658_at
177413_s_at
18483284
A_12_P103620
A_12_P110684
A_12_P130411
A_12_P130412
A_12_P130417
CE02711
CE28229
CE_WBGene00004921_A
CE_WBGene00004921_B
CGZ0019122
F31E8.2
F31E8.2a
F31E8.2b_1167-1226_0.958_1_A
F31E8.2b_1277-1336_0.928_4_B
F31E8.2b_809-868_0.926_5_C
F31E8_2aP00970
F31E8_2aP00975
F31E8_2aP01173
F31E8_2bP00863
GO:0016020
WBGene00004921
cea2.c.11779
Participates
as a component of
SYT1 dimer [plasma membrane] (Caenorhabditis elegans)
as an output of
Release of docked dopamine loaded synaptic vesicle (Caenorhabditis elegans)
Release of acetylcholine at the synapse (Caenorhabditis elegans)
Release of noradrenaline at the synapse (Caenorhabditis elegans)
Release of L-Glutamate at the synapse (Caenorhabditis elegans)
Release of GABA at the synapse (Caenorhabditis elegans)
Release of docked serotonin loaded synaptic vesicle (Caenorhabditis elegans)
Other forms of this molecule
SYT1 [clathrin-coated endocytic vesicle membrane]
SYT2 [clathrin-coated endocytic vesicle membrane]
SYT8 [clathrin-coated endocytic vesicle membrane]
SYT8 [plasma membrane]
SYT2 [plasma membrane]
SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane]
SYT1 [clathrin-sculpted glutamate transport vesicle membrane]
SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
SYT1 [clathrin-sculpted monoamine transport vesicle membrane]
Inferred From
SYT1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001022129.1
PRO
P34693
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