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skr-1 [cytosol]
Stable Identifier
R-CEL-174150
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
SKP1, G5ECU1
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Mitotic G2-G2/M phases (Caenorhabditis elegans)
G2/M Transition (Caenorhabditis elegans)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Caenorhabditis elegans)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Caenorhabditis elegans)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SCF-FBXL7 ubiquitinates AURKA (Caenorhabditis elegans)
SCF-FBXL7:AURKA [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SCF:FBXL7 binds AURKA (Caenorhabditis elegans)
SCF-FBXL7:AURKA [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Regulation of PLK1 Activity at G2/M Transition (Caenorhabditis elegans)
Phosphorylated BORA binds SCF-beta-TrCp1/2 (Caenorhabditis elegans)
CUL1:FBXW11:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] (Caenorhabditis elegans)
CUL1:FBXW11:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Caenorhabditis elegans)
CUL1:FBXW11:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] (Caenorhabditis elegans)
CUL1:FBXW11:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Polyubiquitination of substrate (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Neddylation (Caenorhabditis elegans)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
NEDD8-CRL1 E3 ligase complex [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Signaling by WNT (Caenorhabditis elegans)
Degradation of beta-catenin by the destruction complex (Caenorhabditis elegans)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Degradation of ubiquitinated beta catenin by the proteasome (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
Transport of small molecules (Caenorhabditis elegans)
Iron uptake and transport (Caenorhabditis elegans)
SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Caenorhabditis elegans)
SKP1:FBXL5:CUL1:NEDD8 [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:FBXL5 [cytosol] (Caenorhabditis elegans)
skr-1 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:G5ECU1
Gene Names
skr-1
Reference Genes
BioGPS Gene:172775 skr-1
ENSEMBL:WBGene00004807
KEGG Gene (Caenorhabditis elegans):CELE_F46A9.5 skr-1
Monarch:172775 skr-1
NCBI Gene:172775 skr-1
UCSC:G5ECU1 skr-1
Wormbase:WBGene00004807
Reference Transcript
RefSeq:NM_060112.5 skr-1
Other Identifiers
172775
18456012
193777_s_at
A_12_P101919
A_12_P149845
A_12_P149847
CE10580
CE_WBGene00004807_A
CE_WBGene00004807_B
CGZ0021990
F46A9.5
F46A9.5_282-341_0.960_3_B
F46A9.5_404-463_0.936_8_C
F46A9.5_469-528_0.966_1_A
F46A9_5P00209
F46A9_5P00225
F46A9_5P00366
GO:0006511
GO:0030163
WBGene00004807
cea2.c.03639
Participates
as a component of
NEDD8-CRL1 E3 ligase complex [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Caenorhabditis elegans)
SKP1:CUL1:FBXL5 [cytosol] (Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
CUL1:FBXW11:SKP1 [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
skr-1 [nucleoplasm]
Inferred From
SKP1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_492513.1
PRO
G5ECU1
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