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cul-1 [nucleoplasm]
Stable Identifier
R-CEL-187551
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
nucleoplasm
Synonyms
CUL1, Q17389
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle Checkpoints (Caenorhabditis elegans)
G1/S DNA Damage Checkpoints (Caenorhabditis elegans)
p53-Independent G1/S DNA Damage Checkpoint (Caenorhabditis elegans)
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Caenorhabditis elegans)
Ubiquitination of phosphorylated CDC25A (Caenorhabditis elegans)
SCF-BTrCP1,2 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
SCF-FBXW11 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Mitotic G1 phase and G1/S transition (Caenorhabditis elegans)
G1 Phase (Caenorhabditis elegans)
Cyclin D associated events in G1 (Caenorhabditis elegans)
Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Ubiquitination of p130 (RBL2) by SCF (Skp2) (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
G1/S Transition (Caenorhabditis elegans)
Cyclin E associated events during G1/S transition (Caenorhabditis elegans)
SCF(Skp2)-mediated degradation of p27/p21 (Caenorhabditis elegans)
Association of Cks1 with SCF(Skp2) complex (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Ubiquitination of phospho-p27/p21 (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
S Phase (Caenorhabditis elegans)
Cyclin A:Cdk2-associated events at S phase entry (Caenorhabditis elegans)
SCF(Skp2)-mediated degradation of p27/p21 (Caenorhabditis elegans)
Association of Cks1 with SCF(Skp2) complex (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Ubiquitination of phospho-p27/p21 (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Caenorhabditis elegans)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Caenorhabditis elegans)
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
KEAP1-NFE2L2 pathway (Caenorhabditis elegans)
Nuclear events mediated by NFE2L2 (Caenorhabditis elegans)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Caenorhabditis elegans)
BTRC binds p-S344, 347 NFE2L2 (Caenorhabditis elegans)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Caenorhabditis elegans)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Ub,pS335,S338,T NFE2L2 is degraded (Caenorhabditis elegans)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
DNA Replication (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Caenorhabditis elegans)
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional regulation by RUNX2 (Caenorhabditis elegans)
Regulation of RUNX2 expression and activity (Caenorhabditis elegans)
SCF(SKP2) complex binds RUNX2 (Caenorhabditis elegans)
RUNX2:SCF(SKP2) [nucleoplasm] (Caenorhabditis elegans)
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
SCF(SKP2) polyubiquitinates RUNX2 (Caenorhabditis elegans)
RUNX2:SCF(SKP2) [nucleoplasm] (Caenorhabditis elegans)
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
cul-1 [nucleoplasm] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q17389
Gene Names
cul-1
Reference Genes
BioGPS Gene:176466 cul-1
ENSEMBL:WBGene00000836
KEGG:cel:CELE_D2045.6 cul-1
Monarch:176466 cul-1
NCBI Gene:176466 cul-1
UCSC:Q17389 cul-1
Wormbase:WBGene00000836
Wormbase:WBGene00000836 cul-1
Reference Transcript
RefSeq:NM_066908.8 cul-1
Other Identifiers
176466
GO:0002119
GO:0005737
GO:0006511
GO:0006950
GO:0008285
GO:0008340
GO:0008361
GO:0009792
GO:0010564
GO:0010826
GO:0016567
GO:0019005
GO:0030163
GO:0030674
GO:0031146
GO:0031461
GO:0031625
GO:0031647
GO:0042594
GO:0043065
GO:0043066
GO:0043518
GO:0045930
GO:0048856
GO:0051301
GO:0060090
GO:0090128
GO:1902532
Participates
as a component of
SCF (SKP2) complex [nucleoplasm] (Caenorhabditis elegans)
SCF-FBXW11 [nucleoplasm] (Caenorhabditis elegans)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Caenorhabditis elegans)
CUL1:SKP1:SKP2 [nucleoplasm] (Caenorhabditis elegans)
Other forms of this molecule
cul-1 [cytosol]
cul-1 [cytosol]
Inferred From
CUL1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_499309.1
ENSEMBL
WBGene00000836
,
D2045.6.1
,
D2045.6.1
PRO
Q17389
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