Reactome | let-756 [extracellular region]

let-756 [extracellular region]

Stable Identifier

R-CEL-189909

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

FGF21, Q11184

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q11184

Gene Names

let-756

Reference Genes

BioGPS Gene:175909 let-756

ENSEMBL:WBGene00002881

KEGG Gene (Caenorhabditis elegans):CELE_C05D11.4 let-756

Monarch:175909 let-756

NCBI Gene:175909 let-756

UCSC:Q11184 let-756

Wormbase:WBGene00002881

Reference Transcript

RefSeq:NM_066002.4 let-756

Other Identifiers

175909

18508527

188194_at

A_12_P110594

A_12_P135055

A_12_P135056

C05D11.4

C05D11.4_328-387_0.887_33_C

C05D11.4_500-559_0.910_20_A

C05D11.4_731-790_0.914_19_B

C05D11_4P00503

C05D11_4P00691

C05D11_4P01201

CE24786

CE_WBGene00002881_A

CE_WBGene00002881_B

CGZ0002579

GO:0000902

GO:0002119

GO:0003674

GO:0005104

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0007165

GO:0007275

GO:0008083

GO:0008134

GO:0008150

GO:0008543

GO:0016020

GO:0016607

GO:0019899

GO:0019901

GO:0030154

GO:0031345

GO:0040007

GO:0040011

GO:0043226

GO:0048841

GO:0048856

WBGene00002881

cea2.c.16767

This entity regulates

Positively

GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol

Other forms of this molecule

phospho-let-756 [endoplasmic reticulum lumen]

let-756 [endoplasmic reticulum lumen]

let-756 [Golgi lumen]

let-756 [extracellular region]

Inferred From

FGF21 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_498403.1

PRO

Q11184

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P28548	5	kin-10 [extracellular region] (R-CEL-6806508) kin-10 [ficolin-1-rich granule lumen] (R-CEL-6801290) kin-10 [secretory granule lumen] (R-CEL-6801319) kin-10 [nucleoplasm] (R-CEL-6805067) kin-10 [cytosol] (R-CEL-201693)	0.543	3
UniProt:P41932	3	par-5 [cytosol] (R-CEL-1445105) par-5 [nucleoplasm] (R-CEL-450469) par-5 [cytosol] (R-CEL-1445116)	0.543	3
UniProt:P47991	1	rpl-6 [cytosol] (R-CEL-72484)	0.543	3
UniProt:P18334	4	kin-3 [nucleoplasm] (R-CEL-6805065) kin-3 [nucleoplasm] (R-CEL-6805057) kin-3 [cytosol] (R-CEL-201721) kin-3 [cytosol] (R-CEL-201713)	0.543	3
UniProt:Q22054	2	rps-16 [cytosol] (R-CEL-72337) rps-16 [nucleoplasm] (R-CEL-6791196)	0.543	4
UniProt:Q20655	4	ftt-2 [cytosol] (R-CEL-1445105-2) ftt-2 [nucleoplasm] (R-CEL-450469-2) ftt-2 [cytosol] (R-CEL-1445107) ftt-2 [cytosol] (R-CEL-1445116-2)	0.543	3
UniProt:Q21556 Q21556			0.543	4
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.508	2
UniProt:Q09958	1	EBNA1BP2 [nucleoplasm] (R-CEL-8869325)	0.508	2
UniProt:Q18688	11	daf-21 [ficolin-1-rich granule lumen] (R-CEL-6801491) daf-21 [ficolin-1-rich granule lumen] (R-CEL-6801470) daf-21 [extracellular region] (R-CEL-6806463) daf-21 [extracellular region] (R-CEL-3221946) daf-21 [secretory granule lumen] (R-CEL-6801477) daf-21 [secretory granule lumen] (R-CEL-6801515) daf-21 [plasma membrane] (R-CEL-534996) daf-21 [cytosol] (R-CEL-419617) daf-21 [nucleoplasm] (R-CEL-5082401) daf-21 [nucleoplasm] (R-CEL-5082399) daf-21 [cytosol] (R-CEL-192864)	0.508	3
UniProt:G5EDD8 G5EDD8			0.508	3

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