Reactome | phospho-ced-3 [cytosol]

phospho-ced-3 [cytosol]

Stable Identifier

R-CEL-198636-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

p-S196-CASP9(1-416), P42573

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Intracellular signaling by second messengers (Caenorhabditis elegans)
  - PIP3 activates AKT signaling (Caenorhabditis elegans)
    - AKT phosphorylates targets in the cytosol (Caenorhabditis elegans)
      - AKT phosphorylates caspase-9 (Caenorhabditis elegans)
        
        Homologues of p-S196-CASP9(1-416) [cytosol] (Caenorhabditis elegans)
        
        phospho-ced-3 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P42573

Gene Names

ced-3

Reference Genes

BioGPS Gene:178272 ced-3

CTD Gene:178272 ced-3

ENSEMBL:WBGene00000417

KEGG Gene (Caenorhabditis elegans):CELE_C48D1.2 ced-3

Monarch:178272 ced-3

NCBI Gene:178272 ced-3

UCSC:P42573 ced-3

Wormbase:WBGene00000417

Reference Transcript

RefSeq:NM_001268779.1 ced-3

Other Identifiers

174274_at

178272

18550245

194137_at

A_12_P113211

C48D1.2

C48D1.2_1365-1424_0.963_1_A

C48D1.2_772-831_0.914_15_B

C48D1.2_943-1002_0.920_13_C

C48D1_2P00170

C48D1_2P00355

C48D1_2P01221

CE29088

CE_WBGene00000417_A

CGZ0009650

CGZ0009651

GO:0003674

GO:0004197

GO:0006508

GO:0008150

GO:0008219

GO:0008233

GO:0008234

GO:0042981

WBGene00000417

cea2.c.27112

Participates

as a member of

Homologues of p-S196-CASP9(1-416) [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

ced-3 [nucleoplasm]

ced-3 [cytosol]

Inferred From

p-S196-CASP9(1-416) [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 196 (in Homo sapiens)

Coordinate

196

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_001255708.1

IntEnz

3.4.22.60

PRO

P42573

PDB

4M9S, 4M9Y, 4M9R, 4M9Z, 4M9X

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41958	2	ced-9 [mitochondrial outer membrane] (R-CEL-50757) ced-9 [mitochondrial outer membrane] (R-CEL-114236)	0.702	4

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