Reactome | 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region]

3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region]

Stable Identifier

R-CEL-2127376

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

G5EFQ9

Locations in the PathwayBrowser

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Developmental Biology (Caenorhabditis elegans)

- Axon guidance (Caenorhabditis elegans)
  - NCAM signaling for neurite out-growth (Caenorhabditis elegans)
    - NCAM1 interactions (Caenorhabditis elegans)
      - Interaction of NCAM1 with collagens (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        NCAM-1:Collagen complex [plasma membrane] (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)

Extracellular matrix organization (Caenorhabditis elegans)

- Collagen formation (Caenorhabditis elegans)
  - Assembly of collagen fibrils and other multimeric structures (Caenorhabditis elegans)
    - Collagen XI cross-links with collagen II (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - Collagen type XI fibril:Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - Formation of collagen fibres (Caenorhabditis elegans)
      - Collagen fibres [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibre [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Collagen type XI fibre [extracellular region] (Caenorhabditis elegans)
        
        Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - Collagen fibrils [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - Formation of collagen fibrils (Caenorhabditis elegans)
      - Collagen fibrils [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - Tropocollagens [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - Type X collagen associates with collagen type II fibrils (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - Collagen type X:type II fibrils [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
  - Collagen biosynthesis and modifying enzymes (Caenorhabditis elegans)
    - Removal of fibrillar collagen C-propeptides (Caenorhabditis elegans)
      - Tropocollagens [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
- Degradation of the extracellular matrix (Caenorhabditis elegans)
  - Collagen degradation (Caenorhabditis elegans)
    - Collagen type II degradation by MMP1,3,8,13,PRSS2 (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - Collagen type II degradation by MMP15 (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
- FN1 binds Collagen types I-V, VII (Caenorhabditis elegans)
  - Collagen types I-V, VII [extracellular region] (Caenorhabditis elegans)
    - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
      - Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
  - FN1(32-2386):Collagen types I-V, VII [extracellular region] (Caenorhabditis elegans)
    - Collagen types I-V, VII [extracellular region] (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
- Integrin cell surface interactions (Caenorhabditis elegans)
  - Collagen type II binds integrin alpha10beta1 (Caenorhabditis elegans)
    - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
      - Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - Integrin alpha10beta1:Collagen type II fibril:Mg2+ [plasma membrane] (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
- Non-integrin membrane-ECM interactions (Caenorhabditis elegans)
  - DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Caenorhabditis elegans)
    - Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - DDR1 dimer:Collagen type I, II, III, IV, V, XI fibrils [plasma membrane] (Caenorhabditis elegans)
      - Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        Collagen type XI fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type XI [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
  - DDR2 binds collagen type I, II, III, V, X fibrils (Caenorhabditis elegans)
    - Collagen type I, II, III, V, X fibrils [extracellular region] (Caenorhabditis elegans)
      - Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
    - DDR2 dimer:Collagen type I, II, III, V, X fibrils [plasma membrane] (Caenorhabditis elegans)
      - Collagen type I, II, III, V, X fibrils [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
  - Signaling by PDGF (Caenorhabditis elegans)
    - PDGF binds to extracellular matrix proteins (Caenorhabditis elegans)
      - Extracellular matrix ligands [extracellular region] (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
      - PDGF A and B chains:ECM complex [extracellular region] (Caenorhabditis elegans)
        
        Extracellular matrix ligands [extracellular region] (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen type II fibril [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen type II [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-1(II) chains [extracellular region] (Caenorhabditis elegans)
        
        Homologues of 3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)
        
        3x4Hyp-5Hyl-COL2A1(182-1241) [extracellular region] (Caenorhabditis elegans)