Reactome | efn-3 [plasma membrane]

efn-3 [plasma membrane]

Stable Identifier

R-CEL-2682339-3

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

EFNA1, Q19475

Locations in the PathwayBrowser

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Developmental Biology (Caenorhabditis elegans)

- Nervous system development (Caenorhabditis elegans)
  - Axon guidance (Caenorhabditis elegans)
    - EPH-Ephrin signaling (Caenorhabditis elegans)
      - EPH receptors autophosphorylate (Caenorhabditis elegans)
        
        EPH-ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
      - EPH-ephrin mediated repulsion of cells (Caenorhabditis elegans)
        
        EPHA binds TIAM1 (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        SFKs phosphorylate VAV2,3 (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        TIAM1 exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        VAV exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHs bind VAV2,3 (Caenorhabditis elegans)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Caenorhabditis elegans)
        
        p-EPH:ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
      - EPH:EFN dimers tetramerise (Caenorhabditis elegans)
        
        EPH-EFN dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
      - EPH:EFN tetramers oligomerise (Caenorhabditis elegans)
        
        EPH-EFN dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA dimers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        EPH-ephrin oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
      - EPHA-mediated growth cone collapse (Caenorhabditis elegans)
        
        NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs:p-Y179-NGEF [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Caenorhabditis elegans)
        
        p-EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
      - EPHAs bind EFNAs (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)
        
        EPHAs:EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        EFNAs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of EFNA1 [plasma membrane] (Caenorhabditis elegans)
        
        efn-3 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q19475

Gene Names

efn-3

Reference Genes

BioGPS Gene:184508 efn-3

CTD Gene:184508 efn-3

ENSEMBL:WBGene00001164

KEGG Gene (Caenorhabditis elegans):CELE_F15A2.5 efn-3

Monarch:184508 efn-3

NCBI Gene:184508 efn-3

UCSC:Q19475 efn-3

Wormbase:WBGene00001164

Reference Transcript

RefSeq:NM_077849.3 efn-3

Other Identifiers

178940_at

184508

18623823

A_12_P100830

CE05634

CE_WBGene00001164_A

CGZ0016403

F15A2.5

F15A2.5_204-263_0.930_3_A

F15A2_5P00033

F15A2_5P00248

F15A2_5P00334

GO:0000902

GO:0003674

GO:0005575

GO:0005886

GO:0007165

GO:0007411

GO:0008150

GO:0016020

GO:0030154

GO:0040011

GO:0046875

GO:0048013

GO:0048856

WBGene00001164

cea2.i.52679

Participant Of

hasMember

Homologues of EFNA1 [plasma membrane]

Other forms of this molecule

phospho-efn-3 [plasma membrane]

efn-3 [plasma membrane]

Inferred From

EFNA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_510250.3

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