Reactome | hpr-17 [nucleoplasm]

hpr-17 [nucleoplasm]

Stable Identifier

R-CEL-3008665

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

RAD17, G5EGG2

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - G2/M Checkpoints (Caenorhabditis elegans)
    - Activation of ATR in response to replication stress (Caenorhabditis elegans)
      - Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Caenorhabditis elegans)
        
        Rad17-RFC complex bound to DNA [nucleoplasm] (Caenorhabditis elegans)
        
        RAD17:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        hpr-17 [nucleoplasm] (Caenorhabditis elegans)
        
        Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Caenorhabditis elegans)
        
        Rad17-RFC complex bound to DNA [nucleoplasm] (Caenorhabditis elegans)
        
        RAD17:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        hpr-17 [nucleoplasm] (Caenorhabditis elegans)

DNA Repair (Caenorhabditis elegans)

- DNA Double-Strand Break Repair (Caenorhabditis elegans)
  - Homology Directed Repair (Caenorhabditis elegans)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Caenorhabditis elegans)
      - Processing of DNA double-strand break ends (Caenorhabditis elegans)
        
        ATR phosphorylates RPA2 (Caenorhabditis elegans)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Caenorhabditis elegans)
        
        RAD17:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        hpr-17 [nucleoplasm] (Caenorhabditis elegans)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Caenorhabditis elegans)
        
        RAD17:RFC [nucleoplasm] (Caenorhabditis elegans)
        
        hpr-17 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EGG2

Gene Names

hpr-17

Reference Genes

BioGPS Gene:174958 hpr-17

CTD Gene:174958 hpr-17

ENSEMBL:WBGene00001998

Monarch:174958 hpr-17

NCBI Gene:174958 hpr-17

Wormbase:WBGene00001998

Reference Transcript

RefSeq:NM_064392.5 hpr-17

Other Identifiers

174958

18498446

188147_s_at

A_12_P107398

CE17738

CE_WBGene00001998_A

CE_WBGene00001998_C

CGZ0019188

F32A11.2

F32A11.2_1086-1145_0.926_17_B

F32A11.2_1330-1389_0.934_10_A

F32A11.2_975-1034_0.895_34_C

F32A11_2P00114

F32A11_2P00467

F32A11_2P00839

GO:0006281

WBGene00001998

cea2.c.11896

Participates

as a component of

RAD17:RFC [nucleoplasm] (Caenorhabditis elegans)

Inferred From

RAD17 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_496793.1

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