Reactome | smo-1 [nucleoplasm]

smo-1 [nucleoplasm]

Stable Identifier

R-CEL-3782555

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

K554-TRIM28-G97-SUMO1, P55853

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - SUMOylation (Caenorhabditis elegans)
    - SUMO E3 ligases SUMOylate target proteins (Caenorhabditis elegans)
      - SUMOylation of transcription cofactors (Caenorhabditis elegans)
        
        TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 (Caenorhabditis elegans)
        
        SUMO1:TRIM28:ZNF350 [nucleoplasm] (Caenorhabditis elegans)
        
        6SUMO1:TRIM28 [nucleoplasm] (Caenorhabditis elegans)
        
        smo-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P55853

Gene Names

smo-1

Reference Genes

BioGPS Gene:266820 smo-1

ENSEMBL:WBGene00004888

KEGG Gene (Caenorhabditis elegans):CELE_K12C11.2 smo-1

Monarch:266820 smo-1

NCBI Gene:266820 smo-1

UCSC:P55853 smo-1

Wormbase:WBGene00004888

Reference Transcript

RefSeq:NM_058441.4 smo-1

Other Identifiers

18458193

187669_at

266820

A_12_P113449

A_12_P130201

CE18056

CE_WBGene00004888_A

CE_WBGene00004888_B

CE_WBGene00004888_C

CGZ0029344

GO:0000003

GO:0000122

GO:0000278

GO:0002119

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005815

GO:0005819

GO:0005856

GO:0006464

GO:0007049

GO:0007059

GO:0007080

GO:0007275

GO:0008150

GO:0009058

GO:0009790

GO:0009792

GO:0010468

GO:0016605

GO:0016925

GO:0019899

GO:0031386

GO:0031647

GO:0034502

GO:0034641

GO:0040011

GO:0042592

GO:0042802

GO:0043226

GO:0044389

GO:0045892

GO:0046716

GO:0048856

GO:0051276

GO:0051306

GO:0070194

GO:0071965

GO:0110039

GO:0140014

K12C11.2

K12C11.2_209-268_0.519_16_C

K12C11.2_7-66_0.938_2_B

K12C11.2_73-132_0.944_1_A

K12C11_2P00027

K12C11_2P00042

K12C11_2P00167

WBGene00004888

cea2.c.05105

Participates

as a component of

6SUMO1:TRIM28 [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

smo-1 [nucleoplasm]

Inferred From

K804-TRIM28-G97-SUMO1 [nucleoplasm] (Homo sapiens)

K575-TRIM28-G97-SUMO1 [nucleoplasm] (Homo sapiens)

K750-TRIM28-G97-SUMO1 [nucleoplasm] (Homo sapiens)

K676-TRIM28-G97-SUMO1 [nucleoplasm] (Homo sapiens)

K554-TRIM28-G97-SUMO1 [nucleoplasm] (Homo sapiens)

K779-TRIM28-G97-SUMO1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via sumoylated lysine at 97 and 554 (in Homo sapiens)

Coordinate

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_490842.1

PRO

P55853

PDB

5XQM

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q94420	1	mel-26 [nucleoplasm] (R-CEL-5635035-5)	0.778	5
UniProt:P55853	50	smo-1 [nucleoplasm] (R-CEL-3968375) smo-1 [nucleoplasm] (R-CEL-4085334) smo-1 [nucleoplasm] (R-CEL-4551713) smo-1 [nucleoplasm] (R-CEL-3782555) smo-1 [nucleoplasm] (R-CEL-3900210) smo-1 [nucleoplasm] (R-CEL-4085344) smo-1 [nucleoplasm] (R-CEL-3900212) smo-1 [nucleoplasm] (R-CEL-3899290) smo-1 [nucleoplasm] (R-CEL-3730764) smo-1 [nucleoplasm] (R-CEL-4085364) smo-1 [nucleoplasm] (R-CEL-4086058) smo-1 [nucleoplasm] (R-CEL-4090362) smo-1 [nucleoplasm] (R-CEL-3730875) smo-1 [nucleoplasm] (R-CEL-4641311) smo-1 [nucleoplasm] (R-CEL-4641306) smo-1 [nucleoplasm] (R-CEL-4641341) smo-1 [nucleoplasm] (R-CEL-4615836) smo-1 [nucleoplasm] (R-CEL-4570527) smo-1 [nucleoplasm] (R-CEL-3826645) smo-1 [nucleoplasm] (R-CEL-3826574) smo-1 [nucleoplasm] (R-CEL-3730884) smo-1 [nucleoplasm] (R-CEL-4568845) smo-1 [nucleoplasm] (R-CEL-4551631) smo-1 [nucleoplasm] (R-CEL-4570452) smo-1 [nucleoplasm] (R-CEL-3730735) smo-1 [nucleoplasm] (R-CEL-4341090) smo-1 [nucleoplasm] (R-CEL-4755424) smo-1 [nucleoplasm] (R-CEL-4719434) smo-1 [nucleoplasm] (R-CEL-4546379) smo-1 [nucleoplasm] (R-CEL-4755434) smo-1 [nucleoplasm] (R-CEL-4341069) smo-1 [nucleoplasm] (R-CEL-4719410) smo-1 [nucleoplasm] (R-CEL-4551761) smo-1 [nucleoplasm] (R-CEL-3730622) smo-1 [nucleoplasm] (R-CEL-3730616) smo-1 [nucleoplasm] (R-CEL-877304) smo-1 [nucleoplasm] (R-CEL-2990831) smo-1 [nucleoplasm] (R-CEL-3730796) smo-1 [nucleoplasm] (R-CEL-3730823) smo-1 [nucleoplasm] (R-CEL-4570549) smo-1 [nucleoplasm] (R-CEL-8956370) smo-1 [nucleoplasm] (R-CEL-4615956) smo-1 [nucleoplasm] (R-CEL-4615877) smo-1 [nucleoplasm] (R-CEL-4616032) smo-1 [nucleoplasm] (R-CEL-4616028) smo-1 [nucleoplasm] (R-CEL-4570462) smo-1 [nucleoplasm] (R-CEL-3730738) smo-1 [nucleoplasm] (R-CEL-3730646) smo-1 [nucleoplasm] (R-CEL-3730731) smo-1 [nucleoplasm] (R-CEL-4719426)	0.712	4
UniProt:Q95017	3	ubc-9 [nucleoplasm] (R-CEL-912481) ubc-9 [nucleoplasm] (R-CEL-4085358) ubc-9 [nucleoplasm] (R-CEL-3730617)	0.712	5
UniProt:Q23158	8	atn-1 [extracellular region] (R-CEL-349725) atn-1 [extracellular region] (R-CEL-349722) atn-1 [extracellular region] (R-CEL-349729) atn-1 [platelet alpha granule lumen] (R-CEL-349727) atn-1 [platelet alpha granule lumen] (R-CEL-349724) atn-1 [platelet alpha granule lumen] (R-CEL-198240) atn-1 [cytosol] (R-CEL-354096) atn-1 [cytosol] (R-CEL-390562)	0.621	3
UniProt:P90740 FAN1			0.621	3
UniProt:O16299 FIGL1			0.553	2
UniProt:Q18994	1	eif-2bepsilon [cytosol] (R-CEL-72523)	0.488	2
UniProt:Q9NF71	1	RCOR1 [nucleoplasm] (R-CEL-996766-4)	0.488	2
UniProt:Q9NA84 Q9NA84			0.488	2
UniProt:O45548 O45548			0.488	2
UniProt:H2KYD4 H2KYD4			0.488	2
UniProt:W03G1.4 Q3V5H0			0.488	2
UniProt:Q17987 Q17987			0.488	2
UniProt:G5EFR3	1	ZCCHC6 [cytosol] (R-CEL-8941313)	0.488	2
UniProt:Q9GZG5 Q9GZG5			0.488	2
UniProt:G5EF87 G5EF87			0.488	2
UniProt:A5JYT9	1	row-1 [nucleoplasm] (R-CEL-480506)	0.488	2
UniProt:Q20952	5	add-2 [cytosol] (R-CEL-5226994) add-2 [cytosol] (R-CEL-420043) add-2 [cytosol] (R-CEL-202890) add-2 [cytosol] (R-CEL-202891) add-2 [cytosol] (R-CEL-201623)	0.488	2
UniProt:Q94361	5	gei-17 [nucleoplasm] (R-CEL-2993785) gei-17 [nucleoplasm] (R-CEL-3968415-2) gei-17 [nucleoplasm] (R-CEL-2993764-2) gei-17 [nucleoplasm] (R-CEL-877307-2) gei-17 [nucleoplasm] (R-CEL-2993789-2)	0.488	2

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