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tkr-1 [plasma membrane]
Stable Identifier
R-CEL-380103
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
plasma membrane
Synonyms
TACR1, Q03566
Locations in the PathwayBrowser
Expand all
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
GPCRs that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
BAR domain proteins recruit dynamin (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
Cargo recognition for clathrin-mediated endocytosis (Caenorhabditis elegans)
ARBB recruits GPCRs into clathrin-coated pits (Caenorhabditis elegans)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
ARRB bind GPCRs (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
Endophilins recruit synaptojanins to the clathrin-coated pit (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
CLASP proteins:cargo [plasma membrane] (Caenorhabditis elegans)
ARRB:ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
tkr-1 [plasma membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q03566
Gene Names
tkr-1
Reference Genes
BioGPS Gene:192055 tkr-1
ENSEMBL:WBGene00006576
KEGG Gene (Caenorhabditis elegans):CELE_C38C10.1 tkr-1
Monarch:192055 tkr-1
NCBI Gene:192055 tkr-1
Wormbase:WBGene00006576
Reference Transcript
RefSeq:NM_066663.4 tkr-1
Other Identifiers
18509846
192055
193134_at
A_12_P110703
C38C10.1
C38C10.1_136-195_0.866_30_C
C38C10.1_374-433_0.909_10_A
C38C10.1_55-114_0.867_29_B
C38C10_1P00181
C38C10_1P00389
C38C10_1P00855
CE00104
CE_WBGene00006576_A
CE_WBGene00006576_B
CGZ0008101
GO:0004930
GO:0004995
GO:0005886
GO:0007186
GO:0016020
GO:0023052
GO:0060089
WBGene00006576
cea2.i.18976
Participates
as a candidate of
ARRB-binding GPCRs [plasma membrane] (Caenorhabditis elegans)
as a member of
GPCRs that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
Other forms of this molecule
tkr-1 [clathrin-coated endocytic vesicle membrane]
tkr-1 [plasma membrane]
tkr-1 [plasma membrane]
Inferred From
TACR1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_499064.2
PRO
Q03566
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