Reactome | wrm-1 [plasma membrane]

wrm-1 [plasma membrane]

Stable Identifier

R-CEL-437260-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

JUP, Q10953

Locations in the PathwayBrowser

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Developmental Biology (Caenorhabditis elegans)

- Keratinization (Caenorhabditis elegans)
  - Formation of the cornified envelope (Caenorhabditis elegans)
    - PERP binds desmosomes (Caenorhabditis elegans)
      - Desmosome [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of JUP [plasma membrane] (Caenorhabditis elegans)
        
        wrm-1 [plasma membrane] (Caenorhabditis elegans)
      - Desmosome:PERP [plasma membrane] (Caenorhabditis elegans)
        
        Desmosome [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of JUP [plasma membrane] (Caenorhabditis elegans)
        
        wrm-1 [plasma membrane] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
  - Signaling by VEGF (Caenorhabditis elegans)
    - VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
      - VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
        
        PAK1-3 phosphorylates VE-cadherin (Caenorhabditis elegans)
        
        VE-cadherin-Catenin complex [plasma membrane] (Caenorhabditis elegans)
        
        Beta-catenin/gamma catenin [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of JUP [plasma membrane] (Caenorhabditis elegans)
        
        wrm-1 [plasma membrane] (Caenorhabditis elegans)
        
        p-S665-VE-cadherin-Catenin complex [plasma membrane] (Caenorhabditis elegans)
        
        Beta-catenin/gamma catenin [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of JUP [plasma membrane] (Caenorhabditis elegans)
        
        wrm-1 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q10953

Gene Names

wrm-1

Reference Genes

BioGPS Gene:175802 wrm-1

ENSEMBL:WBGene00006943

Monarch:175802 wrm-1

NCBI Gene:175802 wrm-1

UCSC:Q10953 wrm-1

Wormbase:WBGene00006943

Reference Transcript

RefSeq:NM_065835.6 wrm-1

Other Identifiers

175615_s_at

175802

18507984

187995_s_at

A_12_P119087

B0336.1

B0336.1_1761-1820_0.911_6_B

B0336.1_2029-2088_0.910_7_C

B0336.1_2168-2227_0.936_1_A

B0336_1P01107

B0336_1P01543

B0336_1P02077

CE26743

CE_WBGene00006943_A

CE_WBGene00006943_B

CGZ0000779

GO:0005515

GO:0007155

GO:0045296

WBGene00006943

cea2.p.54917

Participates

as a member of

Homologues of JUP [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

wrm-1 [cytosol]

wrm-1 [specific granule lumen]

wrm-1 [extracellular region]

wrm-1 [ficolin-1-rich granule lumen]

Inferred From

JUP [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_498236.1

PRO

Q10953

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9U9Y8	3	phospho-p-T298-NLK [nucleoplasm] (R-CEL-4411376) phospho-p-T298-NLK [cytosol] (R-CEL-4411398) NLK [cytosol] (R-CEL-4411330)	0.761	8
UniProt:Q10666	6	phospho-pop-1 [nucleoplasm] (R-CEL-4411389) phospho-pop-1 [nucleoplasm] (R-CEL-4411392) pop-1 [nucleoplasm] (R-CEL-3299543) pop-1 [nucleoplasm] (R-CEL-5228649) pop-1 [nucleoplasm] (R-CEL-3214972) pop-1 [nucleoplasm] (R-CEL-201923)	0.553	2

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