Reactome | Homologues of SH2D2A [cytosol]

Homologues of SH2D2A [cytosol]

Stable Identifier

R-CEL-4420125-3

Type

Set [DefinedSet]

Species

Caenorhabditis elegans

Compartment

cytosol

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
  - Signaling by VEGF (Caenorhabditis elegans)
    - VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
      - AXL autophosphorylates on Y779 and Y821 (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
      - AXL binds SRC-1 (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
      - Phosphorylation of SRC-1 (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
      - VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
      - p-AXL binds PI3K (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane] (Caenorhabditis elegans)
        
        VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of SH2D2A [cytosol] (Caenorhabditis elegans)

Participants

members

Participates

as a component of

VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] (Caenorhabditis elegans)

Inferred From

SH2D2A [cytosol] (Homo sapiens)