Reactome | atf-7 [nucleoplasm]

atf-7 [nucleoplasm]

Stable Identifier

R-CEL-450336

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

ATF2, Q86MD3

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Cytokine Signaling in Immune system (Caenorhabditis elegans)
  - Signaling by Interleukins (Caenorhabditis elegans)
    - Interleukin-17 signaling (Caenorhabditis elegans)
      - MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
- Innate Immune System (Caenorhabditis elegans)
  - Toll-like Receptor Cascades (Caenorhabditis elegans)
    - Toll Like Receptor 10 (TLR10) Cascade (Caenorhabditis elegans)
      - MyD88 cascade initiated on plasma membrane (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
    - Toll Like Receptor 2 (TLR2) Cascade (Caenorhabditis elegans)
      - Toll Like Receptor TLR1:TLR2 Cascade (Caenorhabditis elegans)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
      - Toll Like Receptor TLR6:TLR2 Cascade (Caenorhabditis elegans)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
    - Toll Like Receptor 3 (TLR3) Cascade (Caenorhabditis elegans)
      - MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
    - Toll Like Receptor 4 (TLR4) Cascade (Caenorhabditis elegans)
      - MyD88-independent TLR4 cascade (Caenorhabditis elegans)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
    - Toll Like Receptor 5 (TLR5) Cascade (Caenorhabditis elegans)
      - MyD88 cascade initiated on plasma membrane (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Caenorhabditis elegans)
      - MyD88 dependent cascade initiated on endosome (Caenorhabditis elegans)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)
    - Toll Like Receptor 9 (TLR9) Cascade (Caenorhabditis elegans)
      - MyD88 dependent cascade initiated on endosome (Caenorhabditis elegans)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Caenorhabditis elegans)
        
        MAP kinase activation (Caenorhabditis elegans)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Caenorhabditis elegans)
        
        Activation of the AP-1 family of transcription factors (Caenorhabditis elegans)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)
        
        atf-7 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q86MD3

Gene Names

atf-7

Reference Genes

BioGPS Gene:175587 atf-7

CTD Gene:175587 atf-7

ENSEMBL:WBGene00000223

Monarch:175587 atf-7

NCBI Gene:175587 atf-7

UCSC:Q86MD3 atf-7

Wormbase:WBGene00000223

Reference Transcript

Other Identifiers

172407_x_at

173892_s_at

175587

18521069

191216_s_at

A_12_P106395

A_12_P141865

A_12_P141866

A_12_P141867

A_12_P141868

A_12_P141869

A_12_P179034

A_12_P179035

A_12_P179036

A_12_P179037

A_12_P179038

C07G2.2

C07G2.2a

C07G2.2b

C07G2.2c_1148-1207_0.923_13_C

C07G2.2c_1179-1238_0.935_9_B

C07G2.2c_1348-1407_0.963_1_A

C07G2_2aP00127

C07G2_2aP00614

C07G2_2aP01169

C07G2_2cP00053

C07G2_2cP00068

C07G2_2cP00072

CE19687

CE19688

CE_WBGene00000223_A

CE_WBGene00000223_C

CGZ0003237

CGZ0003241

GO:0003700

GO:0006351

GO:0006355

GO:0140110

WBGene00000223

cea2.3.02100

cea2.c.17097

cea2.d.00435

Participates

as an input of

Phosphorylated MAPKs phosphorylate ATF-2 (Caenorhabditis elegans)

Other forms of this molecule

phospho-atf-7 [nucleoplasm]

Inferred From

ATF2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_497913.1, NP_001021161.1, NP_497914.2, NP_001129834.1

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