Reactome | CDK9 [nucleoplasm]

CDK9 [nucleoplasm]

Stable Identifier

R-CEL-51801

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

Q9TVL3

Locations in the PathwayBrowser

Expand all

Signal Transduction (Caenorhabditis elegans)

- Signaling by Nuclear Receptors (Caenorhabditis elegans)
  - ESR-mediated signaling (Caenorhabditis elegans)
    - Estrogen-dependent gene expression (Caenorhabditis elegans)
      - p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Caenorhabditis elegans)
        
        CDK9 [nucleoplasm] (Caenorhabditis elegans)
        
        MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Caenorhabditis elegans)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Caenorhabditis elegans)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Caenorhabditis elegans)
        
        CDK9 [nucleoplasm] (Caenorhabditis elegans)
        
        MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Caenorhabditis elegans)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Caenorhabditis elegans)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Caenorhabditis elegans)
        
        CDK9 [nucleoplasm] (Caenorhabditis elegans)
- Signaling by TGFB family members (Caenorhabditis elegans)
  - Signaling by TGF-beta Receptor Complex (Caenorhabditis elegans)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Caenorhabditis elegans)
        
        CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Caenorhabditis elegans)
        
        P-TEFb complex [nucleoplasm] (Caenorhabditis elegans)
        
        CDK9 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9TVL3

Reference Genes

BioGPS Gene:173023

ENSEMBL:WBGene00000410

Monarch:173023

NCBI Gene:173023

UCSC:Q9TVL3

Wormbase:WBGene00000410

Reference Transcript

Other Identifiers

173023

18457459

193890_s_at

A_12_P105796

A_12_P112232

A_12_P149590

A_12_P158920

A_12_P158921

CE18824

CE23826

CE_WBGene00000410_A

CE_WBGene00000410_B

CGZ0026743

CGZ0026744

GO:0003824

GO:0004672

GO:0005524

GO:0006468

GO:0016740

GO:0036211

GO:0140096

H25P06.2

H25P06.2a

H25P06.2b

H25P06.2b_1231-1290_0.924_4_A

H25P06.2b_1387-1446_0.925_3_B

H25P06.2b_829-888_0.914_7_C

H25P06_2aP00032

H25P06_2aP00204

H25P06_2aP01106

H25P06_2bP01363

H25P06_2bP01371

WBGene00000410

cea2.d.31447

cea2.p.13253

Participates

as an input of

Formation of P-TEFb complex (Caenorhabditis elegans)

as a component of

Inferred From

CDK9 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_492906.2, NP_492907.2

IntEnz

2.7.11.22

PRO

Q9TVL3

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q17549 Q17549			0.488	2

Cite Us!