Reactome | rmh-2 [nucleoplasm]

rmh-2 [nucleoplasm]

Stable Identifier

R-CEL-5685949

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

RMI1, G5EF82

Locations in the PathwayBrowser

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DNA Repair (Caenorhabditis elegans)

- DNA Double-Strand Break Repair (Caenorhabditis elegans)
  - Homology Directed Repair (Caenorhabditis elegans)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Caenorhabditis elegans)
      - Processing of DNA double-strand break ends (Caenorhabditis elegans)
        
        EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Caenorhabditis elegans)
        
        3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Caenorhabditis elegans)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Caenorhabditis elegans)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        rmh-2 [nucleoplasm] (Caenorhabditis elegans)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Caenorhabditis elegans)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        rmh-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Long-range resection of DNA DSBs by EXO1 or DNA2 (Caenorhabditis elegans)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Caenorhabditis elegans)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Caenorhabditis elegans)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        rmh-2 [nucleoplasm] (Caenorhabditis elegans)
        
        3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Caenorhabditis elegans)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Caenorhabditis elegans)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Caenorhabditis elegans)
        
        rmh-2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EF82

Gene Names

rmh-2

Reference Genes

BioGPS Gene:179383 rmh-2

CTD Gene:179383 rmh-2

ENSEMBL:WBGene00011576

KEGG Gene (Caenorhabditis elegans):CELE_T07C12.12 rmh-2

Monarch:179383 rmh-2

NCBI Gene:179383 rmh-2

Wormbase:WBGene00011576

Reference Transcript

RefSeq:NM_171521.7 rmh-2

Other Identifiers

179383

183013_at

18595674

A_12_P106666

CE31601

CE_WBGene00011576_A

CGZ0033880

GO:0000003

GO:0000166

GO:0000712

GO:0000724

GO:0003674

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006259

GO:0006950

GO:0007049

GO:0007059

GO:0008150

GO:0016604

GO:0031422

GO:0032991

GO:0034641

GO:0043226

T07C12.12

T07C12.12_436-495_0.820_39_C

T07C12.12_468-527_0.851_18_A

T07C12.3

T07C12_12P00689

T07C12_12P01075

T07C12_12P01404

WBGene00011576

cea2.d.05390

cea2.p.124001

Participant Of

hasComponent

BLM:TOP3A:RMI1:RMI2 [nucleoplasm]

Inferred From

RMI1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_741607.1