Reactome | GPI-CD59 [ER to Golgi transport vesicle membrane]

GPI-CD59 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-CEL-5689801

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

ER to Golgi transport vesicle membrane

Synonyms

A3FPJ6

Locations in the PathwayBrowser

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Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPII-mediated vesicle transport (Caenorhabditis elegans)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Caenorhabditis elegans)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Nucleotide exchange on RAB1 (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Vesicle budding (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
    - COPII-mediated vesicle transport (Caenorhabditis elegans)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Caenorhabditis elegans)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
      - COPII coat binds TRAPPCII and RAB1:GDP (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
      - Nucleotide exchange on RAB1 (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
      - Vesicle budding (Caenorhabditis elegans)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)
        
        GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:A3FPJ6

Reference Genes

BioGPS Gene:6418676

ENSEMBL:WBGene00045248

KEGG Gene (Caenorhabditis elegans):CELE_ZK180.7

Monarch:6418676

NCBI Gene:6418676

UCSC:A3FPJ6

Wormbase:WBGene00045248

Reference Transcript

RefSeq:NM_001129362.2

Other Identifiers

18547136

6418676

A_12_P144615

A_12_P144616

A_12_P144617

A_12_P165449

A_12_P165450

A_12_P165451

A_12_P165452

A_12_P165453

CGZ0056502

GO:0016020

WBGene00045248

ZK180.7

ZK180.7_146-205_0.894_3_C

ZK180.7_30-89_0.914_1_A

ZK180.7_335-394_0.899_2_B

Participates

as a member of

Homologues of GPI-CD59 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)

Other forms of this molecule

cleaved GPI-LYPD2 [extracellular region]

cleaved GPI-LYPD1 [extracellular region]

GPI-LYPD1 [plasma membrane]

GPI-LYPD2 [plasma membrane]

CD59 [tertiary granule membrane]

CD59 [specific granule membrane]

GPI-CD59 [Golgi membrane]

GPI-CD59 [transport vesicle]

GPI-CD59 [endoplasmic reticulum-Golgi intermediate compartment membrane]

GPI-CD59 [endoplasmic reticulum membrane]

CD59 [plasma membrane]

Inferred From

GPI-CD59 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Modified Residues

Name

L-asparagine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 102 (in Homo sapiens)

Coordinate

102

Modification

GPI-anchor amidated amino acid carboxyl end residue(1−)

PsiMod Name

L-asparagine amide

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to L-asparagine amide.

Cross References

RefSeq

NP_001122834.1

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