Reactome | phospho-sgk-1 [cytosol]

phospho-sgk-1 [cytosol]

Stable Identifier

R-CEL-6795449

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

p-T256,S422-SGK1, Q2PJ68

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional Regulation by TP53 (Caenorhabditis elegans)
      - Regulation of TP53 Activity (Caenorhabditis elegans)
        
        Regulation of TP53 Expression and Degradation (Caenorhabditis elegans)
        
        Regulation of TP53 Degradation (Caenorhabditis elegans)
        
        PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
        
        phospho-sgk-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q2PJ68

Gene Names

sgk-1

Reference Genes

BioGPS Gene:181697 sgk-1

CTD Gene:181697 sgk-1

ENSEMBL:WBGene00004789

KEGG Gene (Caenorhabditis elegans):CELE_W10G6.2 sgk-1

Monarch:181697 sgk-1

NCBI Gene:181697 sgk-1

UCSC:Q2PJ68 sgk-1

Wormbase:WBGene00004789

Reference Transcript

Other Identifiers

181697

18632982

192233_at

A_12_P105652

CE14798

CE_WBGene00004789_A

CE_WBGene00004789_C

CGZ0039045

GO:0000166

GO:0002119

GO:0003674

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005547

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005886

GO:0006464

GO:0006468

GO:0007165

GO:0007275

GO:0008150

GO:0008289

GO:0016020

GO:0016301

GO:0016310

GO:0016324

GO:0016740

GO:0018105

GO:0035556

GO:0043167

GO:0043226

GO:0046872

GO:0048382

GO:0048856

GO:1904508

W10G6.2

W10G6.2b_1044-1103_0.930_1_A

W10G6.2b_1210-1269_0.928_2_B

W10G6.2b_869-928_0.924_3_C

W10G6_2aP00315

W10G6_2aP00668

W10G6_2aP01021

W10G6_2bP00024

W10G6_2bP00346

WBGene00004789

cea2.p.156089

Participant Of

output

PDPK1 phosphorylates SGK1

Other forms of this molecule

sgk-1 [cytosol]

phospho-sgk-1 [nucleoplasm]

sgk-1 [cytosol]

phospho-sgk-1 [cytosol]

Inferred From

p-T256,S422-SGK1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 422 (in Homo sapiens)

Coordinate

422

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 256 (in Homo sapiens)

Coordinate

256

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_001041299.1, NP_001041298.1

IntEnz

2.7.11.1

PRO

Q2PJ68

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O16850	17	phospho-daf-16 [nucleoplasm] (R-CEL-5687010) phospho-daf-16 [nucleoplasm] (R-CEL-5692651) phospho-daf-16 [cytosol] (R-CEL-5687014) daf-16 [nucleoplasm] (R-CEL-6782501) daf-16 [cytosol] (R-CEL-5687032) daf-16 [nucleoplasm] (R-CEL-9620514) daf-16 [nucleoplasm] (R-CEL-199300) daf-16 [nucleoplasm] (R-CEL-5690183) daf-16 [nucleoplasm] (R-CEL-199305) daf-16 [nucleoplasm] (R-CEL-9614396) phospho-daf-16 [nucleoplasm] (R-CEL-9614995) phospho-daf-16 [nucleoplasm] (R-CEL-199314) phospho-daf-16 [nucleoplasm] (R-CEL-199306) phospho-daf-16 [nucleoplasm] (R-CEL-199289) phospho-daf-16 [cytosol] (R-CEL-9614413) phospho-daf-16 [cytosol] (R-CEL-211158) phospho-daf-16 [cytosol] (R-CEL-9614415)	0.676	3
UniProt:Q9XTG7	14	phospho-akt-2 [cytosol] (R-CEL-8848757-2) phospho-akt-2 [plasma membrane] (R-CEL-199430-2) phospho-akt-2 [cytosol] (R-CEL-198634-2) phospho-akt-2 [cytosol] (R-CEL-3009370-2) phospho-akt-2 [nucleoplasm] (R-CEL-198357-2) phospho-akt-2 [nucleoplasm] (R-CEL-3009365-2) akt-2 [cytosol] (R-CEL-58252-2) akt-2 [cytosol] (R-CEL-2976007-2) akt-2 [plasma membrane] (R-CEL-199416-2) akt-2 [plasma membrane] (R-CEL-2976006-2) phospho-akt-2 [plasma membrane] (R-CEL-377265-2) phospho-akt-2 [plasma membrane] (R-CEL-3009363-2) phospho-akt-2 [cytosol] (R-CEL-198356-2) phospho-akt-2 [cytosol] (R-CEL-3009367-2)	0.567	3
UniProt:Q17941	20	phospho-akt-1 [cytosol] (R-CEL-8848757) phospho-akt-1 [plasma membrane] (R-CEL-199430) phospho-akt-1 [cytosol] (R-CEL-198634) phospho-akt-1 [cytosol] (R-CEL-3009370) phospho-akt-1 [cytosol] (R-CEL-202066) phospho-akt-1 [nucleoplasm] (R-CEL-198357) phospho-akt-1 [nucleoplasm] (R-CEL-3009365) phospho-akt-1 [nucleoplasm] (R-CEL-202087) akt-1 [cytosol] (R-CEL-58252) akt-1 [cytosol] (R-CEL-2976007) akt-1 [cytosol] (R-CEL-49859) akt-1 [plasma membrane] (R-CEL-199416) akt-1 [plasma membrane] (R-CEL-2976006) akt-1 [plasma membrane] (R-CEL-202053) phospho-akt-1 [plasma membrane] (R-CEL-377265) phospho-akt-1 [plasma membrane] (R-CEL-3009363) phospho-akt-1 [plasma membrane] (R-CEL-2317312) phospho-akt-1 [cytosol] (R-CEL-198356) phospho-akt-1 [cytosol] (R-CEL-166800) phospho-akt-1 [cytosol] (R-CEL-3009367)	0.567	3

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