Reactome | ZC3H8 [nucleoplasm]

ZC3H8 [nucleoplasm]

Stable Identifier

R-CEL-6807406

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

Q22805

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        LEC [nucleoplasm] (Caenorhabditis elegans)
        
        ZC3H8 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        LEC [nucleoplasm] (Caenorhabditis elegans)
        
        ZC3H8 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        LEC [nucleoplasm] (Caenorhabditis elegans)
        
        ZC3H8 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        LEC [nucleoplasm] (Caenorhabditis elegans)
        
        ZC3H8 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        LEC [nucleoplasm] (Caenorhabditis elegans)
        
        ZC3H8 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        LEC [nucleoplasm] (Caenorhabditis elegans)
        
        ZC3H8 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q22805

Reference Genes

BioGPS Gene:177643

CTD Gene:177643

ENSEMBL:WBGene00020827

Monarch:177643

NCBI Gene:177643

UCSC:Q22805

Wormbase:WBGene00020827

Reference Transcript

RefSeq:NM_069034.5

Other Identifiers

174600_at

177643

183481_s_at

18556668

A_12_P120187

CE07550

CE_WBGene00020827_A

CE_WBGene00020827_C

CGZ0036882

GO:0003723

GO:0005515

GO:0005634

GO:0006351

GO:0006355

GO:0043226

GO:0045892

GO:0046872

T26A8.4

T26A8.4_1460-1519_0.958_1_C

T26A8.4_516-575_0.840_83_B

T26A8.4_656-715_0.852_72_A

T26A8_4P00553

T26A8_4P00908

T26A8_4P01592

WBGene00020827

cea2.p.99359

Participates

as a component of

LEC [nucleoplasm] (Caenorhabditis elegans)

Inferred From

ZC3H8 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_501435.1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9N2Z7	3	wwp-1 [cytosol] (R-CEL-975995) wwp-1 [cytosol] (R-CEL-976037) wwp-1 [cytosol] (R-CEL-6807279)	0.488	2