Reactome | ints-4 [nucleoplasm]

ints-4 [nucleoplasm]

Stable Identifier

R-CEL-6807462

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

INTS4, O18167

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-4 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O18167

Gene Names

ints-4

Reference Genes

BioGPS Gene:173238 ints-4

ENSEMBL:WBGene00012234

Monarch:173238 ints-4

NCBI Gene:173238 ints-4

UCSC:O18167 ints-4

Wormbase:WBGene00012234

Reference Transcript

RefSeq:NM_060995.7 ints-4

Other Identifiers

173238

179584_at

18460546

A_12_P113168

CE25138

CE_WBGene00012234_A

CE_WBGene00012234_B

CE_WBGene00012234_C

CGZ0038291

W04A4.5

W04A4.5_1561-1620_0.804_68_B

W04A4.5_2824-2883_0.898_14_C

W04A4.5_2955-3014_0.933_3_A

W04A4_5P01794

W04A4_5P02188

W04A4_5P03050

WBGene00012234

cea2.p.19187

Participates

as a component of

Integrator [nucleoplasm] (Caenorhabditis elegans)

Inferred From

INTS4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_493396.1

PRO

O18167