Reactome | RPAP2 [nucleoplasm]

RPAP2 [nucleoplasm]

Stable Identifier

R-CEL-6810227

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

P30641

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        RPAP2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        RPAP2 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        RPAP2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        RPAP2 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        RPAP2 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        RPAP2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P30641

Reference Genes

BioGPS Gene:176267

ENSEMBL:WBGene00011143

Monarch:176267

NCBI Gene:176267

UCSC:P30641

Wormbase:WBGene00011143

Reference Transcript

RefSeq:NM_066582.4

Other Identifiers

176267

18514504

186973_at

A_12_P111000

CE00290

CE_WBGene00011143_A

CE_WBGene00011143_B

CE_WBGene00011143_C

CGZ0031433

GO:0003824

GO:0008420

GO:0016787

GO:0043175

GO:0140096

R08D7.2

R08D7.2_1144-1203_0.928_2_B

R08D7.2_1317-1376_0.958_1_A

R08D7.2_901-960_0.900_6_C

R08D7_2P00039

R08D7_2P00326

R08D7_2P01269

WBGene00011143

cea2.p.70330

Participates

as a component of

Inferred From

RPAP2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_498983.1

IntEnz

3.1.3.16

PRO

P30641