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rpn-10 [cytosol]
Stable Identifier
R-CEL-68800
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
PSMD4, O61742
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle Checkpoints (Caenorhabditis elegans)
G1/S DNA Damage Checkpoints (Caenorhabditis elegans)
p53-Dependent G1/S DNA damage checkpoint (Caenorhabditis elegans)
p53-Dependent G1 DNA Damage Response (Caenorhabditis elegans)
Stabilization of p53 (Caenorhabditis elegans)
Autodegradation of the E3 ubiquitin ligase COP1 (Caenorhabditis elegans)
Proteasome mediated degradation of COP1 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
p53-Independent G1/S DNA damage checkpoint (Caenorhabditis elegans)
p53-Independent DNA Damage Response (Caenorhabditis elegans)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Caenorhabditis elegans)
Proteolytic degradation of ubiquitinated-Cdc25A (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Mitotic G2-G2/M phases (Caenorhabditis elegans)
G2/M Transition (Caenorhabditis elegans)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Caenorhabditis elegans)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
S Phase (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
CDK-mediated phosphorylation and removal of Cdc6 (Caenorhabditis elegans)
Ubiquitinated Cdc6 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Ubiquitinated Orc1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Ubiquitin-dependent degradation of Cyclin D (Caenorhabditis elegans)
Proteasome mediated degradation of Cyclin D1 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
KEAP1-NFE2L2 pathway (Caenorhabditis elegans)
26S proteasome degrades Ub-NFE2L2 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Cellular response to hypoxia (Caenorhabditis elegans)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Caenorhabditis elegans)
Proteasome proteolyzes ub-HIF-alpha (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
DNA Replication (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
CDK-mediated phosphorylation and removal of Cdc6 (Caenorhabditis elegans)
Ubiquitinated Cdc6 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Ubiquitinated Orc1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen processing-Cross presentation (Caenorhabditis elegans)
Cross-presentation of soluble exogenous antigens (endosomes) (Caenorhabditis elegans)
Proteasomal clevage of exogenous antigen (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
Proteasomal cleavage of substrate (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of polyamines (Caenorhabditis elegans)
Regulation of ornithine decarboxylase (ODC) (Caenorhabditis elegans)
26S proteosome degrades ODC holoenzyme complex (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Deubiquitination (Caenorhabditis elegans)
UCH proteinases (Caenorhabditis elegans)
ADRM1 binds 26S proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteaseome binds UCHL5 (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome:UCHL5 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Ub-specific processing proteases (Caenorhabditis elegans)
ADRM1:26S proteaseome binds USP14 (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome:USP14 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Neddylation (Caenorhabditis elegans)
26S proteasome degrades HIFalpha (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
26S proteasome degrades Ub-NFE2L2 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN stability and activity (Caenorhabditis elegans)
Proteasome degrades polyubiquitinated PTEN (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK6/MAPK4 signaling (Caenorhabditis elegans)
MAPK6 is degraded by the 26S proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
PCP/CE pathway (Caenorhabditis elegans)
Asymmetric localization of PCP proteins (Caenorhabditis elegans)
PRICKLE1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Degradation of beta-catenin by the destruction complex (Caenorhabditis elegans)
Degradation of ubiquitinated beta catenin by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
TCF dependent signaling in response to WNT (Caenorhabditis elegans)
Degradation of DVL (Caenorhabditis elegans)
Ubiquitinated DVL1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
Transport of small molecules (Caenorhabditis elegans)
ABC-family proteins mediated transport (Caenorhabditis elegans)
misfolded CFTR is degraded by the 26S proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
rpn-10 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:O61742
Gene Names
rpn-10
Reference Genes
BioGPS Gene:172977 rpn-10
ENSEMBL:WBGene00004466
Monarch:172977 rpn-10
NCBI Gene:172977 rpn-10
UCSC:O61742 rpn-10
Wormbase:WBGene00004466
Reference Transcript
RefSeq:NM_060408.4 rpn-10
Other Identifiers
172977
173653_at
18464587
188262_s_at
A_12_P109801
A_12_P144970
A_12_P144971
B0205.3
B0205.3_297-356_0.919_15_C
B0205.3_797-856_0.945_4_B
B0205.3_948-1007_0.949_1_A
B0205_3P00085
B0205_3P00303
B0205_3P00521
CE26355
CE_WBGene00004466_A
CE_WBGene00004466_C
CGZ0000318
GO:0006511
GO:0008540
GO:0030163
WBGene00004466
cea2.c.00113
Participates
as a component of
26S proteasome [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
rpn-10 [nucleoplasm]
Inferred From
PSMD4 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_492809.1
PRO
O61742
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