Reactome | rpl-32 [cytosol]

rpl-32 [cytosol]

Stable Identifier

R-CEL-72456

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RPL32, Q22716

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        60S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rpl-32 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q22716

Gene Names

rpl-32

Reference Genes

BioGPS Gene:174443 rpl-32

ENSEMBL:WBGene00004446

Monarch:174443 rpl-32

NCBI Gene:174443 rpl-32

UCSC:Q22716 rpl-32

Wormbase:WBGene00004446

Reference Transcript

RefSeq:NM_001267265.1 rpl-32

Other Identifiers

173248_s_at

174443

18503767

A_12_P119732

A_12_P175939

CE03709

CE_WBGene00004446_A

CGZ0036551

CGZ0036553

CGZ0036555

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0043226

T24B8.1

T24B8.1a_188-247_0.913_3_A

T24B8.1a_352-411_0.860_6_B

T24B8.1a_98-157_0.756_13_C

T24B8_1P00056

T24B8_1P00107

T24B8_1P00321

WBGene00004446

cea2.c.14409

Participates

as a component of

Inferred From

RPL32 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001254194.1

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