Reactome | FBXO40 [cytosol]

FBXO40 [cytosol]

Stable Identifier

R-CEL-8862612

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

O17324

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Adaptive Immune System (Caenorhabditis elegans)
  - Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
    - Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
      - Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
      - Polyubiquitination of substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
      - Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
      - Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Neddylation (Caenorhabditis elegans)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
        
        CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO40 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O17324

Reference Genes

BioGPS Gene:182497

ENSEMBL:WBGene00015673

KEGG Gene (Caenorhabditis elegans):CELE_C10E2.2

Monarch:182497

NCBI Gene:182497

UCSC:O17324

Wormbase:WBGene00015673

Reference Transcript

RefSeq:NM_078300.4

Other Identifiers

182497

182870_at

18603562

A_12_P104778

C10E2.2

C10E2.2_428-487_0.894_32_A

C10E2.2_573-632_0.892_34_B

C10E2.2_886-945_0.875_47_C

C10E2_2P00126

C10E2_2P00587

C10E2_2P01400

CE08061

CE_WBGene00015673_A

CE_WBGene00015673_B

CGZ0004003

GO:0003824

GO:0005515

GO:0008270

GO:0016740

GO:0046872

GO:0061630

GO:0140096

WBGene00015673

cea2.i.50323

Participates

as a member of

F-box protein [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

FBXO30 [cytosol]

Inferred From

FBXO40 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_510701.2

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