Reactome | cal-5 [nucleoplasm]

cal-5 [nucleoplasm]

Stable Identifier

R-CEL-9016871

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

CALM1, Q18136

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Innate Immune System (Caenorhabditis elegans)
  - C-type lectin receptors (CLRs) (Caenorhabditis elegans)
    - CLEC7A (Dectin-1) signaling (Caenorhabditis elegans)
      - CLEC7A (Dectin-1) induces NFAT activation (Caenorhabditis elegans)
        
        Translocation of CaN:CaM:NFAT to nucleus (Caenorhabditis elegans)
        
        NFAT:CaN:CaM [nucleoplasm] (Caenorhabditis elegans)
        
        CaN:CaM:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)
  - Fc epsilon receptor (FCERI) signaling (Caenorhabditis elegans)
    - FCERI mediated Ca+2 mobilization (Caenorhabditis elegans)
      - Translocation of CaN:CaM:NFAT to nucleus (Caenorhabditis elegans)
        
        NFAT:CaN:CaM [nucleoplasm] (Caenorhabditis elegans)
        
        CaN:CaM:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)

Neuronal System (Caenorhabditis elegans)

- Transmission across Chemical Synapses (Caenorhabditis elegans)
  - Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
    - Activation of NMDA receptors and postsynaptic events (Caenorhabditis elegans)
      - Post NMDA receptor activation events (Caenorhabditis elegans)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Caenorhabditis elegans)
        
        CaMKK autophosphorylates in the nucleus (Caenorhabditis elegans)
        
        CaMKK:CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Intracellular signaling by second messengers (Caenorhabditis elegans)
  - DAG and IP3 signaling (Caenorhabditis elegans)
    - CaM pathway (Caenorhabditis elegans)
      - Calmodulin induced events (Caenorhabditis elegans)
        
        CaMK IV-mediated phosphorylation of CREB (Caenorhabditis elegans)
        
        CaMKK autophosphorylates in the nucleus (Caenorhabditis elegans)
        
        CaMKK:CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)
- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (i) signalling events (Caenorhabditis elegans)
      - Opioid Signalling (Caenorhabditis elegans)
        
        G-protein mediated events (Caenorhabditis elegans)
        
        PLC beta mediated events (Caenorhabditis elegans)
        
        Ca-dependent events (Caenorhabditis elegans)
        
        CaM pathway (Caenorhabditis elegans)
        
        Calmodulin induced events (Caenorhabditis elegans)
        
        CaMK IV-mediated phosphorylation of CREB (Caenorhabditis elegans)
        
        CaMKK autophosphorylates in the nucleus (Caenorhabditis elegans)
        
        CaMKK:CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)
- Signaling by WNT (Caenorhabditis elegans)
  - Beta-catenin independent WNT signaling (Caenorhabditis elegans)
    - Ca2+ pathway (Caenorhabditis elegans)
      - Translocation of NFATC1:CaN:CaM to nucleus (Caenorhabditis elegans)
        
        NFATC1:CaN:CaM [nucleoplasm] (Caenorhabditis elegans)
        
        CaN:CaM:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm] (Caenorhabditis elegans)
        
        CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)
        
        cal-5 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q18136

Gene Names

cal-5

Reference Genes

BioGPS Gene:192083 cal-5

ENSEMBL:WBGene00006861

KEGG Gene (Caenorhabditis elegans):CELE_C24H10.5 cal-5

Monarch:192083 cal-5

NCBI Gene:192083 cal-5

UCSC:Q18136 cal-5

Wormbase:WBGene00006861

Reference Transcript

RefSeq:NM_076463.7 cal-5

Other Identifiers

18620476

192083

193392_at

A_12_P117939

C24H10.5

C24H10.5_127-186_0.925_4_B

C24H10.5_374-433_0.959_1_A

C24H10.5_377-436_0.948_2_C

C24H10_5P00148

C24H10_5P00303

C24H10_5P00323

CE29674

CE_WBGene00006861_A

CE_WBGene00006861_C

CGZ0005767

GO:0005509

WBGene00006861

cea2.c.41795

Participates

as a component of

CALM1:4xCa2+ [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

cal-5 [extracellular region]

cal-5 [cytosol]

cal-5 [extracellular region]

cal-5 [ficolin-1-rich granule lumen]

cal-5 [plasma membrane]

cal-5 [cytosol]

Inferred From

CALM1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_508864.2

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