Reactome | cash-1 [cytosol]

cash-1 [cytosol]

Stable Identifier

R-CEL-9037081

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

STRN, A0A486WY88

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Intracellular signaling by second messengers (Caenorhabditis elegans)
  - PIP3 activates AKT signaling (Caenorhabditis elegans)
    - Negative regulation of the PI3K/AKT network (Caenorhabditis elegans)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Caenorhabditis elegans)
        
        PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
        
        Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
        
        ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
        
        ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Caenorhabditis elegans)
        
        ESRs:STRN:ESTG [cytosol] (Caenorhabditis elegans)
        
        cash-1 [cytosol] (Caenorhabditis elegans)
    - PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
      - Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
        
        ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
        
        ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Caenorhabditis elegans)
        
        ESRs:STRN:ESTG [cytosol] (Caenorhabditis elegans)
        
        cash-1 [cytosol] (Caenorhabditis elegans)
- Signaling by Nuclear Receptors (Caenorhabditis elegans)
  - ESR-mediated signaling (Caenorhabditis elegans)
    - Extra-nuclear estrogen signaling (Caenorhabditis elegans)
      - PTK2 is recruited to methylated ESR1 (Caenorhabditis elegans)
        
        Me260-ESR1:STRN:ESTG: MyrG-pY419 SRC:PI3Kalpha:pY-PTK2 [plasma membrane] (Caenorhabditis elegans)
        
        Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
        
        cash-1 [cytosol] (Caenorhabditis elegans)
        
        Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Caenorhabditis elegans)
        
        cash-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:A0A486WY88

Gene Names

cash-1

Reference Genes

ENSEMBL:WBGene00010631

Wormbase:WBGene00010631

Other Identifiers

174971_at

179445

18572787

189765_at

A_12_P152215

A_12_P152216

A_12_P174262

CE_WBGene00010631_A

CE_WBGene00010631_B

CGZ0028197

GO:0005515

K07C5.8

K07C5.8_1708-1767_0.937_3_C

K07C5.8_1856-1915_0.951_1_A

K07C5.8_1952-2011_0.932_4_B

K07C5_8P00589

K07C5_8P01047

K07C5_8P01221

WBGene00010631

cea2.p.120699

Participates

as a component of

Inferred From

STRN [cytosol] (Homo sapiens)

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