Reactome | FBXO17 [cytosol]

FBXO17 [cytosol]

Stable Identifier

R-CEL-976036

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

Q17962

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Neddylation (Caenorhabditis elegans)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
        
        CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO17 [cytosol] (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO17 [cytosol] (Caenorhabditis elegans)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO17 [cytosol] (Caenorhabditis elegans)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Caenorhabditis elegans)
        
        F-box protein [cytosol] (Caenorhabditis elegans)
        
        FBXO17 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q17962

Reference Genes

BioGPS Gene:259498

CTD Gene:259498

ENSEMBL:WBGene00007574

KEGG:cel:CELE_C14B1.3

Monarch:259498

NCBI Gene:259498

UCSC:Q17962

Wormbase:WBGene00007574

Reference Transcript

RefSeq:NM_065347.4

Other Identifiers

259498

GO:0003824

GO:0005515

GO:0005737

GO:0006516

GO:0016740

GO:0019005

GO:0030163

GO:0031146

GO:0036503

GO:0061630

GO:0140096

GO:1901135

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)

as a member of

F-box protein [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

FBXO2 [cytosol]

FBXO6 [cytosol]

FBXO27 [cytosol]

FBXO44 [cytosol]

Inferred From

FBXO17 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_497748.1

ENSEMBL

C14B1.3.1, WBGene00007574, C14B1.3.1

PRO

Q17962

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:G5ECU1	2	skr-1 [nucleoplasm] (R-CEL-187538) skr-1 [cytosol] (R-CEL-174150)	0.621	3

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