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E3 ligases in proteasomal degradation [cytosol]
Stable Identifier
R-CEL-976075
Type
Set [CandidateSet]
Species
Caenorhabditis elegans
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
Polyubiquitination of substrate (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
Participants
members
cul-1 [cytosol] (Caenorhabditis elegans)
Homologues of RNF19B [cytosol] (Caenorhabditis elegans)
NEDD4L [cytosol] (Caenorhabditis elegans)
siah-1 [cytosol] (Caenorhabditis elegans)
Homologues of SPSB1 [cytosol] (Caenorhabditis elegans)
herc-1 [cytosol] (Caenorhabditis elegans)
RBCK1 [cytosol] (Caenorhabditis elegans)
TRIM21 [cytosol] (Caenorhabditis elegans)
TRIM69 [cytosol] (Caenorhabditis elegans)
ubr-1 [cytosol] (Caenorhabditis elegans)
eel-1 [cytosol] (Caenorhabditis elegans)
madd-2 [cytosol] (Caenorhabditis elegans)
SCF E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
rbpl-1 [cytosol] (Caenorhabditis elegans)
RNF19A [cytosol] (Caenorhabditis elegans)
ZNRF1 [cytosol] (Caenorhabditis elegans)
ZNRF2 [cytosol] (Caenorhabditis elegans)
FBXL4 [cytosol] (Caenorhabditis elegans)
unk-1 [cytosol] (Caenorhabditis elegans)
candidates
sli-1 [cytosol] (Caenorhabditis elegans)
chn-1 [cytosol] (Caenorhabditis elegans)
wwp-1 [cytosol] (Caenorhabditis elegans)
MGRN1 [cytosol] (Caenorhabditis elegans)
NEDD4 [cytosol] (Caenorhabditis elegans)
RNF25 [cytosol] (Caenorhabditis elegans)
TRIM11 [cytosol] (Caenorhabditis elegans)
TRIM63 [cytosol] (Caenorhabditis elegans)
Homologues of SPSB2 [cytosol] (Caenorhabditis elegans)
spsb-1 [cytosol] (Caenorhabditis elegans)
oxi-1 [cytosol] (Caenorhabditis elegans)
etc-1 [cytosol] (Caenorhabditis elegans)
RBX1-CUL2-EloB,C-VHL [cytosol] (Caenorhabditis elegans)
RBX1:CUL3:BTB [cytosol] (Caenorhabditis elegans)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Caenorhabditis elegans)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Caenorhabditis elegans)
APC/C E3 ligase complex [cytosol] (Caenorhabditis elegans)
ubr-4 [cytosol] (Caenorhabditis elegans)
pdr-1 [cytosol] (Caenorhabditis elegans)
FBXO17 [cytosol] (Caenorhabditis elegans)
FBXO27 [cytosol] (Caenorhabditis elegans)
FBXO44 [cytosol] (Caenorhabditis elegans)
ari-2 [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
dcaf-1 [cytosol] (Caenorhabditis elegans)
hecd-1 [cytosol] (Caenorhabditis elegans)
LTN1 [cytosol] (Caenorhabditis elegans)
TRAF7 [cytosol] (Caenorhabditis elegans)
TRIM39 [cytosol] (Caenorhabditis elegans)
TRIM41 [cytosol] (Caenorhabditis elegans)
TRIM50 [cytosol] (Caenorhabditis elegans)
lin-41 [cytosol] (Caenorhabditis elegans)
ufl-1 [cytosol] (Caenorhabditis elegans)
tag-30 [cytosol] (Caenorhabditis elegans)
hecw-1 [cytosol] (Caenorhabditis elegans)
KLHL11 [cytosol] (Caenorhabditis elegans)
mex-3 [cytosol] (Caenorhabditis elegans)
RNF130 [cytosol] (Caenorhabditis elegans)
trul-1 [cytosol] (Caenorhabditis elegans)
UBE3D [cytosol] (Caenorhabditis elegans)
Participant Of
hasComponent
Ag-substrate:E3:E2:Ub [cytosol]
E3:K48-polyubiquitinated substrate [cytosol]
E3:Ub:substrate [cytosol]
input
Interaction of E3 with substrate and E2-Ub complex
output
Release of E3 from polyubiquitinated substrate
Inferred From
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
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