Reactome | rpn-13 [nucleoplasm]

rpn-13 [nucleoplasm]

Stable Identifier

R-CEL-9918361

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

ADRM1, Q09289

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - G1/S DNA Damage Checkpoints (Caenorhabditis elegans)
    - p53-Independent G1/S DNA Damage Checkpoint (Caenorhabditis elegans)
      - Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Caenorhabditis elegans)
        
        Proteolytic degradation of ubiquitinated-Cdc25A (Caenorhabditis elegans)
        
        26S proteasome [nucleoplasm] (Caenorhabditis elegans)
        
        19S regulatory particle [nucleoplasm] (Caenorhabditis elegans)
        
        19S RP base [nucleoplasm] (Caenorhabditis elegans)
        
        rpn-13 [nucleoplasm] (Caenorhabditis elegans)
- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - Mitotic G1 phase and G1/S transition (Caenorhabditis elegans)
    - G1/S Transition (Caenorhabditis elegans)
      - Cyclin E associated events during G1/S transition (Caenorhabditis elegans)
        
        SCF(Skp2)-mediated degradation of p27/p21 (Caenorhabditis elegans)
        
        Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)
        
        26S proteasome [nucleoplasm] (Caenorhabditis elegans)
        
        19S regulatory particle [nucleoplasm] (Caenorhabditis elegans)
        
        19S RP base [nucleoplasm] (Caenorhabditis elegans)
        
        rpn-13 [nucleoplasm] (Caenorhabditis elegans)
  - S Phase (Caenorhabditis elegans)
    - Cyclin A:Cdk2-associated events at S phase entry (Caenorhabditis elegans)
      - SCF(Skp2)-mediated degradation of p27/p21 (Caenorhabditis elegans)
        
        Degradation of ubiquitinated p27/p21 by the 26S proteasome (Caenorhabditis elegans)
        
        26S proteasome [nucleoplasm] (Caenorhabditis elegans)
        
        19S regulatory particle [nucleoplasm] (Caenorhabditis elegans)
        
        19S RP base [nucleoplasm] (Caenorhabditis elegans)
        
        rpn-13 [nucleoplasm] (Caenorhabditis elegans)

Cellular responses to stimuli (Caenorhabditis elegans)

- Cellular responses to stress (Caenorhabditis elegans)
  - Cellular response to chemical stress (Caenorhabditis elegans)
    - KEAP1-NFE2L2 pathway (Caenorhabditis elegans)
      - Nuclear events mediated by NFE2L2 (Caenorhabditis elegans)
        
        GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Caenorhabditis elegans)
        
        Ub,pS335,S338,T NFE2L2 is degraded (Caenorhabditis elegans)
        
        26S proteasome [nucleoplasm] (Caenorhabditis elegans)
        
        19S regulatory particle [nucleoplasm] (Caenorhabditis elegans)
        
        19S RP base [nucleoplasm] (Caenorhabditis elegans)
        
        rpn-13 [nucleoplasm] (Caenorhabditis elegans)

Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by RUNX2 (Caenorhabditis elegans)
      - Regulation of RUNX2 expression and activity (Caenorhabditis elegans)
        
        26S proteasome degrades PolyUb-RUNX2 (Caenorhabditis elegans)
        
        26S proteasome [nucleoplasm] (Caenorhabditis elegans)
        
        19S regulatory particle [nucleoplasm] (Caenorhabditis elegans)
        
        19S RP base [nucleoplasm] (Caenorhabditis elegans)
        
        rpn-13 [nucleoplasm] (Caenorhabditis elegans)
    - Transcriptional regulation by RUNX3 (Caenorhabditis elegans)
      - Regulation of RUNX3 expression and activity (Caenorhabditis elegans)
        
        Polyubiquitinated RUNX3 is degraded by the proteasome (Caenorhabditis elegans)
        
        26S proteasome [nucleoplasm] (Caenorhabditis elegans)
        
        19S regulatory particle [nucleoplasm] (Caenorhabditis elegans)
        
        19S RP base [nucleoplasm] (Caenorhabditis elegans)
        
        rpn-13 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q09289

Gene Names

rpn-13

Reference Genes

BioGPS Gene:3565888 rpn-13

ENSEMBL:WBGene00016981

KEGG:cel:CELE_C56G2.7 rpn-13

Monarch:3565888 rpn-13

NCBI Gene:3565888 rpn-13

UCSC:Q09289 rpn-13

Wormbase:WBGene00016981

Wormbase:WBGene00016981 rpn-13

Reference Transcript

RefSeq:NM_065986.6 rpn-13

Other Identifiers

3565888

GO:0000502

GO:0005634

GO:0005737

GO:0008541

GO:0043248

GO:0061133

GO:0065003

GO:0070628

GO:0098772

GO:1990381

Participates

as a component of

19S RP base [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

rpn-13 [cytosol]

Inferred From

ADRM1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_498387.2

ENSEMBL

C56G2.7a.1, C56G2.7a.1, WBGene00016981

PRO

Q09289

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