Reactome | CCND3 [nucleoplasm]

CCND3 [nucleoplasm]

Stable Identifier

R-CFA-113835

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

CCND3, A0A8I3NNP3

Locations in the PathwayBrowser

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Cell Cycle (Canis familiaris)

- Cell Cycle, Mitotic (Canis familiaris)
  - Mitotic G1 phase and G1/S transition (Canis familiaris)
    - G1 Phase (Canis familiaris)
      - Cyclin D associated events in G1 (Canis familiaris)
        
        CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Canis familiaris)
        
        CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        CDK4/6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D3:Cdk4 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D3:Cdk6 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3:CDK4 inhibitors (CCND3) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3:CDK6 inhibitors (CCND3) [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Drug-mediated inhibition of CDK4/CDK6 activity (Canis familiaris)
        
        CDK4 inhibitors bind CDK4 (Canis familiaris)
        
        p-T172-CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3:CDK4 inhibitors (CCND3) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        CDK6 inhibitors bind CDK6 (Canis familiaris)
        
        p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3:CDK6 inhibitors (CCND3) [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        p-T172-CDK4:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        p-T177-CDK6:CCND3 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Canis familiaris)
        
        CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Canis familiaris)
        
        CDK4,CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Canis familiaris)
        
        CDK4/6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        CDK4:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D3:Cdk4 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        CDK6:CCND [nucleoplasm] (Canis familiaris)
        
        Cyclin D3:Cdk6 [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)
        
        Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Canis familiaris)
        
        Cyclin D [nucleoplasm] (Canis familiaris)
        
        CCND3 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NNP3

Gene Names

CCND3

Reference Genes

BioGPS Gene:608847 CCND3

ENSEMBL:ENSCAFG00845016058.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845016058.1 CCND3

Monarch:608847 CCND3

NCBI Gene:608847 CCND3

Reference Transcript

RefSeq:XM_859764.3 CCND3

Other Identifiers

608847

CfaAffx.3336.1.S1_at

GO:0000082

GO:0000122

GO:0000278

GO:0000307

GO:0001934

GO:0002376

GO:0003824

GO:0004693

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0007165

GO:0016740

GO:0019901

GO:0023052

GO:0036211

GO:0042098

GO:0042127

GO:0043226

GO:0051726

GO:0061575

GO:0097130

GO:0098772

GO:0140096

Participates

as an input of

MAPK6 binds CCND3 (Canis familiaris)

as a component of

as a member of

CCND3,(CCND1,CCND2) [nucleoplasm] (Canis familiaris)

as a candidate of

Cyclin D [nucleoplasm] (Canis familiaris)

Other forms of this molecule

CCND3 [cytosol]

Inferred From

CCND3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_864857.2

OpenTargets

ENSG00000112576

Ensembl

ENSCAFG00845016058, ENSCAFT00845028739, ENSCAFP00845022621

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