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VHL:EloB,C:CUL2:RBX1 [nucleoplasm]
Stable Identifier
R-CFA-1234141
Type
Complex
Species
Canis familiaris
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to hypoxia (Canis familiaris)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Canis familiaris)
Nuclear VBC complex ubiquitinylates HIF-alpha (Canis familiaris)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Canis familiaris)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Canis familiaris)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CUL2 [nucleoplasm]
(Canis familiaris)
RBX1 [nucleoplasm]
(Canis familiaris)
VBC Complex [nucleoplasm]
(Canis familiaris)
Participates
as a component of
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Canis familiaris)
as an input of
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Canis familiaris)
Inferred From
VHL:EloB,C:CUL2:RBX1 [nucleoplasm]
(Homo sapiens)
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