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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
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ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
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How do I search ?
Details Panel
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Analyse gene expression
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WDR5 [nucleoplasm]
Stable Identifier
R-CFA-1629838
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
WDR5, A0A8I3NH93
Locations in the PathwayBrowser
Expand all
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
HATs acetylate histones (Canis familiaris)
NSL acetylates histone H4 (Canis familiaris)
NSL (PHF20) [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
PKMTs methylate histone lysines (Canis familiaris)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Canis familiaris)
Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Canis familiaris)
SETD3, SETD7, WHSC1L1, Core MLL complex [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Canis familiaris)
WHSC1L1, Core MLL complex, SMYD3, SETD3 [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
RMTs methylate histone arginines (Canis familiaris)
WDR5 binds Me2sR3-replicative histone H3 (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WDR5:Me2sR3-histone H3 [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
Epigenetic regulation of gene expression (Canis familiaris)
Formation of WDR5-containing histone-modifying complexes (Canis familiaris)
BOD1L1 binds SET1A complex (Canis familiaris)
BOD1L1:SET1A complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1A complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
CXXC1 and WDR82 bind SET1A complex (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
CXXC1 and WDR82 bind SET1B complex (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the GCN5-ATAC complex (Canis familiaris)
GCN5-ATAC complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the MLL1 complex (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the MLL2 complex (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the MLL4 complex (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the NSL complex (Canis familiaris)
NSL [nucleoplasm] (Canis familiaris)
NSL (PHF20) [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
NSL (PHF20L1) [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the PCAF-ATAC complex (Canis familiaris)
PCAF-ATAC complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the SET1A complex (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Formation of the SET1B complex (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
HCFC1 binds SET1A complex (Canis familiaris)
SET1A complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex:WDR82:CXXC1:HCFC1 [nucleoplasm] (Canis familiaris)
SET1A complex:WDR82:CXXC1 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
HCFC1, HCFC2 bind the MLL1:MEN1 complex (Canis familiaris)
MLL1 complex,MLL1 complex:MEN1 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL1 complex:MEN1 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL1 complex,MLL1 complex:MEN1:HCFC1,HCFC2 [nucleoplasm] (Canis familiaris)
MLL1 complex:HCFC1 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL1 complex:HCFC2 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL1 complex:MEN1:HCFC1 [nucleoplasm] (Canis familiaris)
MLL1 complex:MEN1 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL1 complex:MEN1:HCFC2 [nucleoplasm] (Canis familiaris)
MLL1 complex:MEN1 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MEN1 binds MLL1 complex (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL1 complex:MEN1 [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MEN1 binds MLL2 complex (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex:MEN1 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL4 complex (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4-ASCOM [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional regulation by RUNX1 (Canis familiaris)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Core MLL complex [nucleoplasm] (Canis familiaris)
MLL1 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL2 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
MLL4 complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1A complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
SET1B complex [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Neddylation (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Canis familiaris)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Canis familiaris)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Canis familiaris)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Canis familiaris)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Canis familiaris)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Canis familiaris)
DCAF protein [nucleoplasm] (Canis familiaris)
WDR5 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NH93
Gene Names
WDR5
Reference Genes
ENSEMBL:ENSCAFG00845011994.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845011994.1 WDR5
Other Identifiers
608113
CfaAffx.30346.1.S1_s_at
GO:0000122
GO:0000123
GO:0001501
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005975
GO:0006094
GO:0006325
GO:0006351
GO:0006355
GO:0006357
GO:0016740
GO:0035064
GO:0035097
GO:0036211
GO:0042393
GO:0042800
GO:0043226
GO:0044545
GO:0044665
GO:0044666
GO:0045722
GO:0045815
GO:0045995
GO:0048188
GO:0048856
GO:0051302
GO:0051571
GO:0051726
GO:0071339
GO:0090043
GO:0140096
GO:0140672
Participates
as a member of
DCAF protein [nucleoplasm] (Canis familiaris)
as an input of
Formation of the NSL complex (Canis familiaris)
Formation of the GCN5-ATAC complex (Canis familiaris)
Formation of the PCAF-ATAC complex (Canis familiaris)
WDR5 binds Me2sR3-replicative histone H3 (Canis familiaris)
as a component of
NSL (PHF20L1) [nucleoplasm] (Canis familiaris)
NSL (PHF20) [nucleoplasm] (Canis familiaris)
GCN5-ATAC complex [nucleoplasm] (Canis familiaris)
PCAF-ATAC complex [nucleoplasm] (Canis familiaris)
WDR5:Me2sR3-histone H3 [nucleoplasm] (Canis familiaris)
WRAD complex [nucleoplasm] (Canis familiaris)
Inferred From
WDR5 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000196363
Ensembl
ENSCAFP00845016778
,
ENSCAFG00845011994
,
ENSCAFT00845021334
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