Reactome | NDUFS3 [mitochondrial matrix]

NDUFS3 [mitochondrial matrix]

Stable Identifier

R-CFA-163927

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial matrix

Synonyms

NDUFS3, F1P9Y3

Locations in the PathwayBrowser

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Metabolism (Canis familiaris)

- The citric acid (TCA) cycle and respiratory electron transport (Canis familiaris)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Canis familiaris)
    - Respiratory electron transport (Canis familiaris)
      - Complex I biogenesis (Canis familiaris)
        
        IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        NDUF subunits bind to form the IP subcomplex (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 [mitochondrial inner membrane] (Canis familiaris)
        
        IP subcomplex [mitochondrial matrix] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFS3 [mitochondrial matrix] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1P9Y3

Gene Names

NDUFS3

Reference Genes

ENSEMBL:ENSCAFG00000008411

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000008411 NDUFS3

Other Identifiers

475978

CfaAffx.13337.1.S1_s_at

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005743

GO:0005747

GO:0008137

GO:0008150

GO:0016020

GO:0016491

GO:0016651

GO:0032991

GO:0043226

GO:0055114

Participant Of

input

NDUF subunits bind to form the IP subcomplex

hasComponent

Inferred From

NDUFS3 [mitochondrial matrix] (Homo sapiens)

Cross References

OpenTargets

ENSG00000213619

Ensembl

ENSCAFT00000013355, ENSCAFP00000012358, ENSCAFG00000008411

VGNC

43708

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