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Shelterin complex [nucleoplasm]
Stable Identifier
R-CFA-174898
Type
Complex
Species
Canis familiaris
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Chromosome Maintenance (Canis familiaris)
Telomere Maintenance (Canis familiaris)
Extension of Telomeres (Canis familiaris)
Telomere C-strand (Lagging Strand) Synthesis (Canis familiaris)
Disassociation of Processive Complex and Completed Telomere End (Canis familiaris)
Extended And Processed Telomere End [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Polymerase switching on the C-strand of the telomere (Canis familiaris)
Formation of Processive Complex on the C-strand of the telomere (Canis familiaris)
Processive complex loaded on telomere [nucleoplasm] (Canis familiaris)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Canis familiaris)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive synthesis on the C-strand of the telomere (Canis familiaris)
Formation of C-strand Okazaki fragments (Canis familiaris)
Processive complex loaded on telomere [nucleoplasm] (Canis familiaris)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Formation of the Flap Intermediate on the C-strand (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Joining of adjacent Okazaki fragments of the C-strand (Canis familiaris)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Removal of the Flap Intermediate from the C-strand (Canis familiaris)
RPA binds to the Flap on the C-strand (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Recruitment of DNA2 endonuclease to the C strand (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Removal of remaining Flap from the C-strand (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomere C-strand synthesis initiation (Canis familiaris)
DNA polymerase:primase binds G-strand of the telomere (Canis familiaris)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Canis familiaris)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Canis familiaris)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Canis familiaris)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomere Extension By Telomerase (Canis familiaris)
Alignment Of The RNA Template On The Telomeric Chromosome End (Canis familiaris)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Canis familiaris)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
CDK2:CCNA phosphorylates TERF2 (Canis familiaris)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Elongation Of The Telomeric Chromosome End (Canis familiaris)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Elongation of Extended Telomeric Chromosome End (Canis familiaris)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
PP6-PPP6R3 dephosphorylates TERF2 (Canis familiaris)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Canis familiaris)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Canis familiaris)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Canis familiaris)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Inhibition of DNA recombination at telomere (Canis familiaris)
ATRX:DAXX binds to subtelomeric chromosomal regions (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
DNA Damage/Telomere Stress Induced Senescence (Canis familiaris)
Telomere shortening during replicative exhaustion (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
DNA Repair (Canis familiaris)
Base Excision Repair (Canis familiaris)
Base-Excision Repair, AP Site Formation (Canis familiaris)
Depurination (Canis familiaris)
Cleavage of the damaged purine (Canis familiaris)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Canis familiaris)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
Recognition and association of DNA glycosylase with site containing an affected purine (Canis familiaris)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Shelterin complex [nucleoplasm] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ACD [nucleoplasm]
(Canis familiaris)
POT1 [nucleoplasm]
(Canis familiaris)
TERF1 homodimer [nucleoplasm]
(Canis familiaris)
TERF2 homodimer [nucleoplasm]
(Canis familiaris)
x 2
TERF2IP [nucleoplasm]
(Canis familiaris)
TINF2 [nucleoplasm]
(Canis familiaris)
Participates
as a component of
AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Canis familiaris)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Canis familiaris)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Canis familiaris)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Canis familiaris)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Canis familiaris)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Canis familiaris)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Canis familiaris)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Canis familiaris)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Canis familiaris)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Canis familiaris)
Extended And Processed Telomere End [nucleoplasm] (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
as an output of
Telomere shortening during replicative exhaustion (Canis familiaris)
Inferred From
Shelterin complex [nucleoplasm]
(Homo sapiens)
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