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p-7Y ALK dimer [plasma membrane]
Stable Identifier
R-CFA-201549
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ALK (Canis familiaris)
ALK autophosphorylation (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK binds JAK3 (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:JAK3 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK binds PLCG1 (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:PLCG1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK binds SHC1 (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:SHC1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK dimer binds IRS1 (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:IRS1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK phosphorylates IRS1 (Canis familiaris)
Active ALK:IRS1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:pY-IRS1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK phosphorylates JAK3 (Canis familiaris)
Active ALK:JAK3 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:p-Y980 JAK3 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK phosphorylates PLCG1 (Canis familiaris)
Active ALK:PLCG1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:p-4Y PLCG1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK phosphorylates SHC1 (Canis familiaris)
Active ALK:SHC1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:p-3Y SHC1 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK recruits PI3K (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:PI3K [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
MDK and PTN in ALK signaling (Canis familiaris)
PTPRZ dephosphorylates ligand-bound ALK dimers (Canis familiaris)
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PI3K synthesizes PIP3 downstream of ALK (Canis familiaris)
Active ALK:PI3K [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTPN6 dephosphorylates JAK3 (Canis familiaris)
Active ALK:JAK3 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Active ALK:p-Y980 JAK3 [plasma membrane] (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
STAT3 is phosphorylated downstream of active ALK (Canis familiaris)
Active ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
p-7Y ALK dimer [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-p-7Y-ALK [plasma membrane]
(Canis familiaris)
Participates
as a component of
PTN:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
MDK:p-7Y ALK dimer [plasma membrane] (Canis familiaris)
Inferred From
p-7Y ALK dimer [plasma membrane]
(Homo sapiens)
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