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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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Developer's Zone
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Pathway Diagrams
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Icon Library Guidelines
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Computationally inferred events
FAQ
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Citing us
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Analyse gene list
Analyse gene expression
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CSK [cytosol]
Stable Identifier
R-CFA-203776
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
A0A8I3P4Z0
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Platelet Aggregation (Plug Formation) (Canis familiaris)
Integrin signaling (Canis familiaris)
Activated integrin alphaIIb beta3 binds SHC1 (Canis familiaris)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Clustering of Integrin alphaIIb beta3 complexes (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3 activation (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Release of CSK from SRC (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Canis familiaris)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
SHC1 dissociates from integrin alphaIIb beta3 (Canis familiaris)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
PD-1 signaling (Canis familiaris)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Canis familiaris)
PTPN6,PTPN11:p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Canis familiaris)
p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Canis familiaris)
LCK, CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Interaction of SHP-1 or SHP-2 with phospho PD-1 (Canis familiaris)
PTPN6,PTPN11:p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Canis familiaris)
p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Canis familiaris)
LCK, CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Canis familiaris)
LCK, CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Phosphorylation of PD-1 (Canis familiaris)
LCK, CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Canis familiaris)
LCK, CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
TCR signaling (Canis familiaris)
Phosphorylation of CD3 and TCR zeta chains (Canis familiaris)
Inactivation of Lck by Csk (Canis familiaris)
Csk:p-PAG [plasma membrane] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Interaction of Csk with PAG (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Csk:p-PAG [plasma membrane] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
PTPN22 dissociates from CSK (Canis familiaris)
CSK [cytosol] (Canis familiaris)
PTPN22:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
Negative regulation of FLT3 (Canis familiaris)
Active FLT3 binds to CSK (Canis familiaris)
CSK [cytosol] (Canis familiaris)
active FLT3:CSK [plasma membrane] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Integrin signaling (Canis familiaris)
Activated integrin alphaIIb beta3 binds SHC1 (Canis familiaris)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Clustering of Integrin alphaIIb beta3 complexes (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3 activation (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Release of CSK from SRC (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Canis familiaris)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
SHC1 dissociates from integrin alphaIIb beta3 (Canis familiaris)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Focal Adhesion/Focal contacts [plasma membrane] (Canis familiaris)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Canis familiaris)
Focal complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Canis familiaris)
Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
RHOH GTPase cycle (Canis familiaris)
RHOH binds effectors at the plasma membrane (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
RHOH:GTP:RHOH effectors [plasma membrane] (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
CSK [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3P4Z0
Reference Genes
ENSEMBL:ENSCAFG00845017685.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845017685.1
Other Identifiers
487649
CfaAffx.27473.1.S1_at
CfaAffx.27473.1.S1_s_at
GO:0000166
GO:0003824
GO:0004672
GO:0004713
GO:0005515
GO:0005524
GO:0005737
GO:0005886
GO:0005911
GO:0006468
GO:0008285
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0034236
GO:0036211
GO:0042802
GO:0042997
GO:0072659
GO:0140096
Participates
as a member of
RHOH effectors [cytosol] (Canis familiaris)
LCK, CSK [cytosol] (Canis familiaris)
as an output of
Release of CSK from SRC (Canis familiaris)
PTPN22 dissociates from CSK (Canis familiaris)
as an input of
Active FLT3 binds to CSK (Canis familiaris)
Interaction of Csk with PAG (Canis familiaris)
as a component of
active FLT3:CSK [plasma membrane] (Canis familiaris)
PTPN22:CSK [cytosol] (Canis familiaris)
Csk:p-PAG [plasma membrane] (Canis familiaris)
p-Y530-SRC:CSK [cytosol] (Canis familiaris)
Other forms of this molecule
CSK [plasma membrane]
Inferred From
CSK [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSCAFP00845024518
,
ENSCAFT00845031318
,
ENSCAFG00845017685
© 2024
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