Reactome | SEC23A [cytosol]

SEC23A [cytosol]

Stable Identifier

R-CFA-203972

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

SEC23A, J9P1Q5

Locations in the PathwayBrowser

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Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Class I MHC mediated antigen processing & presentation (Canis familiaris)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Canis familiaris)
      - Coat Assembly (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPII-mediated vesicle transport (Canis familiaris)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        CSNK1D phosphorylates SEC23 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        Loss of SAR1B GTPase (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        Nucleotide exchange on RAB1 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC31:SEC13 and v-SNARE recruitment (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        Vesicle budding (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        Cargo concentration in the ER (Canis familiaris)
        
        Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        MIA2 and MIA3 load procollagen VII into COPII vesicles (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC24A,B:SEC23A bind SEC22B (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC4C,D bind GOSR2 and STX5 (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPII-mediated vesicle transport (Canis familiaris)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - COPII coat binds TRAPPCII and RAB1:GDP (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - CSNK1D phosphorylates SEC23 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - Loss of SAR1B GTPase (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - Nucleotide exchange on RAB1 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - SEC31:SEC13 and v-SNARE recruitment (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - Vesicle budding (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
    - Cargo concentration in the ER (Canis familiaris)
      - Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23:SEC24 [cytosol] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - MIA2 and MIA3 load procollagen VII into COPII vesicles (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - SEC24A,B:SEC23A bind SEC22B (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
      - SEC4C,D bind GOSR2 and STX5 (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23A [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9P1Q5

Gene Names

SEC23A

Reference Genes

BioGPS Gene:480295 SEC23A

ENSEMBL:ENSCAFG00000013826

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000013826 SEC23A

Monarch:480295 SEC23A

NCBI Gene:480295 SEC23A

Reference Transcript

RefSeq:XM_845739.4 SEC23A

Other Identifiers

480295

CfaAffx.21365.1.S1_s_at

GO:0000139

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0006810

GO:0006886

GO:0006888

GO:0008150

GO:0008270

GO:0012507

GO:0015031

GO:0016020

GO:0016192

GO:0019898

GO:0030127

GO:0030134

GO:0031410

GO:0032991

GO:0043167

GO:0043226

GO:0046872

GO:0048471

GO:0061024

GO:0070971

GO:0072659

GO:0090110

GO:0090114

Participates

as a component of

as an input of

Other forms of this molecule

phospho-SEC23A [cytosol]

SEC23A [ER to Golgi transport vesicle membrane]

SEC23A [endoplasmic reticulum membrane]

Inferred From

SEC23A [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_850832.3

OpenTargets

ENSG00000100934

Ensembl

ENSCAFG00000013826, ENSCAFT00000047366, ENSCAFP00000039480

VGNC

45969

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