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Integrin alphaVbeta3 [plasma membrane]
Stable Identifier
R-CFA-210216
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to mechanical stimuli (Canis familiaris)
Response of endothelial cells to shear stress (Canis familiaris)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Canis familiaris)
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Extracellular matrix organization (Canis familiaris)
ECM proteoglycans (Canis familiaris)
Dentin matrix protein 1 binds integrin alphaVbeta3 (Canis familiaris)
DMP1:Integrin alphVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Canis familiaris)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
TNC:Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Canis familiaris)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VTN:Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Elastic fibre formation (Canis familiaris)
Fibrillin-1 binds integrins (Canis familiaris)
Fibrilin-1:Fibrilin-binding integrins [plasma membrane] (Canis familiaris)
Fibrilin-binding integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Fibrilin-binding integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Molecules associated with elastic fibres (Canis familiaris)
Latent TGF-beta-1 binds integrins (Canis familiaris)
LAP1 binding-integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Canis familiaris)
LAP1 binding-integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Latent TGF-beta-3 binds integrins (Canis familiaris)
LAP3-binding integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Canis familiaris)
LAP3-binding integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin cell surface interactions (Canis familiaris)
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Canis familiaris)
COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Canis familiaris)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Canis familiaris)
Canstatin:Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Canis familiaris)
Endostatin:Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Canis familiaris)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] (Canis familiaris)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Interaction of integrin alphaVbeta3 with Fibrillin (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:IBSP [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Interaction of integrin alphaVbeta3 with PECAM1 (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Interaction of integrin alphaVbeta3 with Tenascin (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Interaction of integrin alphaVbeta3 with von Willbrand Factor (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:VWF multimer [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Tetrastatin binds integrin alphaVbeta3 (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Tetrastatin:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Canis familiaris)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Tumstatin:Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Canis familiaris)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VTN:Integrin alphaVbeta3, 5, 8 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Non-integrin membrane-ECM interactions (Canis familiaris)
Syndecan interactions (Canis familiaris)
Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Canis familiaris)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Syndecan-1:Integrin alpha2beta1 (alpha6beta4) [plasma membrane] (Canis familiaris)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
PECAM1 interactions (Canis familiaris)
Interaction of integrin alphaVbeta3 with PECAM1 (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
PTK2beta binds alphaVbeta3 (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
SRC-1 phosphorylates PTK2-beta (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Signaling by TGFB family members (Canis familiaris)
Signaling by TGF-beta Receptor Complex (Canis familiaris)
TGF-beta receptor signaling activates SMADs (Canis familiaris)
Latent TGF-beta-1 binds integrins (Canis familiaris)
LAP1 binding-integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Canis familiaris)
LAP1 binding-integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Latent TGF-beta-3 binds integrins (Canis familiaris)
LAP3-binding integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Canis familiaris)
LAP3-binding integrins [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ITGAV [plasma membrane]
(Canis familiaris)
ITGB3 [plasma membrane]
(Canis familiaris)
Participates
as a member of
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Canis familiaris)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Canis familiaris)
Fibrilin-binding integrins [plasma membrane] (Canis familiaris)
Integrins [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Canis familiaris)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Canis familiaris)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Canis familiaris)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Canis familiaris)
LAP1 binding-integrins [plasma membrane] (Canis familiaris)
LAP3-binding integrins [plasma membrane] (Canis familiaris)
as an input of
Dentin matrix protein 1 binds integrin alphaVbeta3 (Canis familiaris)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Canis familiaris)
Interaction of integrin alphaVbeta3 with Tenascin (Canis familiaris)
Interaction of integrin alphaVbeta3 with Fibrillin (Canis familiaris)
Interaction of integrin alphaVbeta3 with PECAM1 (Canis familiaris)
Tetrastatin binds integrin alphaVbeta3 (Canis familiaris)
Interaction of integrin alphaVbeta3 with von Willbrand Factor (Canis familiaris)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Canis familiaris)
as a component of
DMP1:Integrin alphVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:IBSP [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Canis familiaris)
Tetrastatin:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
Integrin alphaVbeta3:VWF multimer [plasma membrane] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Canis familiaris)
This entity regulates
Positively
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow
(Canis familiaris)
Inferred From
Integrin alphaVbeta3 [plasma membrane]
(Homo sapiens)
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