Reactome | ITGA8 [plasma membrane]

ITGA8 [plasma membrane]

Stable Identifier

R-CFA-215943

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

ITGA8(39-1063), A0A8I3S0V6

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Signaling by TGFB family members (Canis familiaris)
  - Signaling by TGF-beta Receptor Complex (Canis familiaris)
    - TGF-beta receptor signaling activates SMADs (Canis familiaris)
      - Latent TGF-beta-1 binds integrins (Canis familiaris)
        
        LAP1 binding-integrins [plasma membrane] (Canis familiaris)
        
        Integrin alpha8beta1 [plasma membrane] (Canis familiaris)
        
        ITGA8 [plasma membrane] (Canis familiaris)
        
        LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Canis familiaris)
        
        LAP1 binding-integrins [plasma membrane] (Canis familiaris)
        
        Integrin alpha8beta1 [plasma membrane] (Canis familiaris)
        
        ITGA8 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3S0V6

Gene Names

ITGA8

Reference Genes

ENSEMBL:ENSCAFG00845014426.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845014426.1 ITGA8

Other Identifiers

487119

CfaAffx.7930.1.S1_at

CfaAffx.7943.1.S1_s_at

GO:0001822

GO:0005783

GO:0005886

GO:0007155

GO:0007160

GO:0007229

GO:0008305

GO:0009986

GO:0016020

GO:0023052

GO:0030154

GO:0034446

GO:0043226

GO:0048333

GO:0048856

Participates

as a component of

Integrin alpha8beta1 [plasma membrane] (Canis familiaris)

Inferred From

ITGA8(39-1063) [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000077943

Ensembl

ENSCAFG00845014426, ENSCAFT00845025825, ENSCAFP00845020348