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About
What is Reactome ?
News
Team
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Our Logo
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Table of Contents
DOIs
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ARRB1 [cytosol]
Stable Identifier
R-CFA-264470
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
ARRB1, F1PQM2
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Thrombin signalling through proteinase activated receptors (PARs) (Canis familiaris)
Activated PAR1 binds Beta-arrestin-1 (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Activated PAR1:Beta-arrestin-1 [plasma membrane] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Activated Src activates ERK (Canis familiaris)
Activated PAR1:Beta-arrestin-1:Activated Src:Activated ERK [plasma membrane] (Canis familiaris)
Activated PAR1:Beta-arrestin-1 [plasma membrane] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Activated PAR1:Beta-arrestin-1:Src:ERK [plasma membrane] (Canis familiaris)
Activated PAR1:Beta-arrestin-1 [plasma membrane] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Activation of beta-arrestin-1-bound Src kinase (Canis familiaris)
Activated PAR1:Beta-arrestin-1:Src:ERK [plasma membrane] (Canis familiaris)
Activated PAR1:Beta-arrestin-1 [plasma membrane] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Beta-arrestin-1 acts as scaffold for a PAR1 signalling complex (Canis familiaris)
Activated PAR1:Beta-arrestin-1 [plasma membrane] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Activated PAR1:Beta-arrestin-1:Src:ERK [plasma membrane] (Canis familiaris)
Activated PAR1:Beta-arrestin-1 [plasma membrane] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Deubiquitination (Canis familiaris)
Ub-specific processing proteases (Canis familiaris)
USP33 deubiquitinates CCP110,ARRB (Canis familiaris)
USP33:CCP110,ARRB1,ARRB2 [cytosol] (Canis familiaris)
CCP110,ARRB2,(ARRB1) [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Signaling by Hedgehog (Canis familiaris)
Hedgehog 'on' state (Canis familiaris)
Activation of SMO (Canis familiaris)
SMO translocates to the cilium (Canis familiaris)
SMO dimer:ARRB:KIF3A [endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
BAR domain proteins recruit dynamin (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Cargo recognition for clathrin-mediated endocytosis (Canis familiaris)
ARBB recruits GPCRs into clathrin-coated pits (Canis familiaris)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
ARRB bind GPCRs (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Clathrin recruits PIK3C2A (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Clathrin recruits auxilins to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Dissociation of clathrin-associated proteins (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Endophilins recruit synaptojanins to the clathrin-coated pit (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
F- and N- BAR domain proteins bind the clathrin-coated pit (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
RAB5 and GAPVD1 bind AP-2 (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
SNX9 recruits components of the actin polymerizing machinery (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
ARRB:ARRB-binding GPCRs [plasma membrane] (Canis familiaris)
ARRB [cytosol] (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
trans-Golgi Network Vesicle Budding (Canis familiaris)
Golgi Associated Vesicle Biogenesis (Canis familiaris)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
trans-Golgi Network Derived Vesicle Uncoating (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
Lysosome Vesicle Biogenesis (Canis familiaris)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)
ARRB1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:F1PQM2
Gene Names
ARRB1
Reference Genes
ENSEMBL:ENSCAFG00000005415
Other Identifiers
485189
ARRB1
ARRB1-204
CfaAffx.9060.1.S1_s_at
ENSCAFG00000005415
ENSCAFP00000008081
ENSCAFT00000008715
EntrezGene:485189
EntrezGene:ARRB1
GO:0001664
GO:0002031
GO:0003674
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006810
GO:0006915
GO:0007165
GO:0008150
GO:0008219
GO:0016192
GO:0031410
GO:0043226
GO:0043547
GO:0045746
GO:0070374
IPR000698
IPR011021
IPR011022
IPR014752
IPR014753
IPR014756
IPR017864
PF00339
PF02752
PR00309
SM01017
UPI0003AE1095
VGNC:38136
XM_005633491
XM_005633493
XM_005633494
XP_005633550
Participant Of
output
trans-Golgi Network Derived Lysosomal Vesicle Uncoating
trans-Golgi Network Derived Vesicle Uncoating
input
Activated PAR1 binds Beta-arrestin-1
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture
hasCandidate
CCP110,ARRB2,(ARRB1) [cytosol]
RAF/MAPK scaffolds [cytosol]
hasComponent
Activated PAR1:Beta-arrestin-1 [plasma membrane]
hasMember
ARRB [cytosol]
Other forms of this molecule
ARRB1 [cytoplasmic vesicle membrane]
ARRB1 [Golgi membrane]
ARRB1 [lysosomal membrane]
ARRB1 [cytosol]
Inferred From
ARRB1 [cytosol] (Homo sapiens)
Cross References
OpenTargets
ENSG00000137486
Ensembl
ENSCAFP00000008081
,
ENSCAFG00000005415
,
ENSCAFT00000008715
VGNC
38136
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