KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel

Stable Identifier
R-CFA-265682
Type
Reaction [transition]
Species
Canis familiaris
Compartment
Synonyms
Closing of Inward Rectifying, ATP-sensitive Potassium Channels (KATP channels)
Locations in the PathwayBrowser
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Participants
Participates
Catalyst Activity

ATP binding activity of KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

This event is regulated
Negatively by
Inferred From
Created
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