Reactome | BCL10 oligomer [cytosol]

BCL10 oligomer [cytosol]

Stable Identifier

R-CFA-2685702

Type

Polymer

Species

Canis familiaris

Compartment

cytosol

Locations in the PathwayBrowser

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Immune System (Canis familiaris)

- Innate Immune System (Canis familiaris)
  - C-type lectin receptors (CLRs) (Canis familiaris)
    - CLEC7A (Dectin-1) signaling (Canis familiaris)
      - BCL10 oligomerizes (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - K63polyUb-TAK1 autophosphorylates (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-p3Y,1S-TAK1 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-p3Y,1S-TAK1 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - MALT1 binds BCL10 (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers:MALT1 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - MALT1 oligomerizes (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers:MALT1 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - TRAF6 binds MALT1 oligomers (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - TRAF6 oligomer autoubiquitinates (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - TRAF6 oligomerizes (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - TRIKA2 binds K63polyUb-TRAF6 oligomer (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane] (Canis familiaris)
        
        p-T231-CARD9:BCL10 oligomers [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
  - Fc epsilon receptor (FCERI) signaling (Canis familiaris)
    - FCERI mediated NF-kB activation (Canis familiaris)
      - Activation of TAK1 complex bound to pUb-TRAF6 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:oligo-K63-poly Ub-TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - Auto-ubiquitination of TRAF6 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        CBM oligomer:TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:oligo-K63-poly Ub-TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - Oligomerization of BCL10 and MALT1 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer [plasma membrane] (Canis familiaris)
        
        CBM oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - Oligomerization of TRAF6 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:TRAF6 [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer:MALT1 oligomer:TRAF6 [cytosol] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        CBM oligomer:TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - Phosphorylation of IKK-beta by TAK1 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:oligo-K63-poly Ub-TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:oligo-K63-poly Ub-TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:oligo-K63-poly Ub-TRAF6 oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
      - Recruitment of TRAF6 to CBM complex by binding to MALT1 (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer [plasma membrane] (Canis familiaris)
        
        CBM oligomer [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)
        
        DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 [plasma membrane] (Canis familiaris)
        
        CBM oligomer:TRAF6 [plasma membrane] (Canis familiaris)
        
        BCL10 oligomer:MALT1 oligomer:TRAF6 [cytosol] (Canis familiaris)
        
        BCL10 oligomer [cytosol] (Canis familiaris)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

repeated unit

BCL10 [cytosol] (Canis familiaris)

Participates

as a component of

Inferred From

BCL10 oligomer [cytosol] (Homo sapiens)

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