Reactome | COP1 [nucleoplasm]

COP1 [nucleoplasm]

Stable Identifier

R-CFA-349454

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

RFWD2, A0A8I3N6U5

Locations in the PathwayBrowser

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Cell Cycle (Canis familiaris)

- Cell Cycle Checkpoints (Canis familiaris)
  - G1/S DNA Damage Checkpoints (Canis familiaris)
    - p53-Dependent G1/S DNA damage checkpoint (Canis familiaris)
      - p53-Dependent G1 DNA Damage Response (Canis familiaris)
        
        Stabilization of p53 (Canis familiaris)
        
        Autodegradation of the E3 ubiquitin ligase COP1 (Canis familiaris)
        
        Phosphorylation of COP1 at Ser-387 by ATM (Canis familiaris)
        
        COP1 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N6U5

Gene Names

COP1

Reference Genes

ENSEMBL:ENSCAFG00845008923.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845008923.1 COP1

Other Identifiers

480060

CfaAffx.22037.1.S1_s_at

GO:0003824

GO:0005515

GO:0010212

GO:0016740

GO:0030163

GO:0031464

GO:0032436

GO:0043161

GO:0061630

GO:0140096

Participates

as a member of

DCAF protein [nucleoplasm] (Canis familiaris)

as an input of

Phosphorylation of COP1 at Ser-387 by ATM (Canis familiaris)

Other forms of this molecule

phospho-COP1 [cytosol]

phospho-COP1 [nucleoplasm]

Inferred From

RFWD2 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000143207

Ensembl

ENSCAFT00845015988, ENSCAFG00845008923, ENSCAFP00845012436